Evidence map›Paper›PMID 38461322›Full record

ArticleScientific reports2024

AI supported fetal echocardiography with quality assessment.

Caroline A Taksoee-Vester, Kamil Mikolaj, Zahra Bashir, Anders N Christensen, Olav B Petersen, Karin Sundberg, Aasa Feragen, Morten B S Svendsen, Mads Nielsen, Martin G Tolsgaard

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Bias in AI models for fetal cardiac screening: the consequences of training predominantly on normal anatomy.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Article
  2. Review
  3. Article
  4. Fetal cardiac remodeling in second trimester in pregnancies with pre-eclampsia and/or fetal growth restriction: deep-learning-based approach using population-wide data.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Caroline A Taksoee-VesterDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ca_tv@hotmail.com.
Kamil MikolajDTU Compute, Technical University of Denmark (DTU), Lyngby, Denmark.
Zahra BashirDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Anders N ChristensenDTU Compute, Technical University of Denmark (DTU), Lyngby, Denmark.
Olav B PetersenDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Karin SundbergCenter of Fetal Medicine, Department of Obstetrics, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Dept. 4071, 2100, Copenhagen, Denmark.
Aasa FeragenDTU Compute, Technical University of Denmark (DTU), Lyngby, Denmark.
Morten B S SvendsenCopenhagen Academy of Medical Education and Simulation (CAMES), Rigshospitalet, Copenhagen, Denmark.
Mads NielsenDepartment of Computer Science, University of Copenhagen, Copenhagen, Denmark.
Martin G TolsgaardDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Funding

Novo Nordisk Fonden NNFSA170030576The Centre for Basic Machine Learning Research in Life Science NNF20OC0062606The Pioneer Centre for AI, DNRF Grant P1
6 · The paper itself

Abstract

This study aimed to develop a deep learning model to assess the quality of fetal echocardiography and to perform prospective clinical validation. The model was trained on data from the 18-22-week anomaly scan conducted in seven hospitals from 2008 to 2018. Prospective validation involved 100 patients from two hospitals. A total of 5363 images from 2551 pregnancies were used for training and validation. The model's segmentation accuracy depended on image quality measured by a quality score (QS). It achieved an overall average accuracy of 0.91 (SD 0.09) across the test set, with images having above-average QS scoring 0.97 (SD 0.03). During prospective validation of 192 images, clinicians rated 44.8% (SD 9.8) of images as equal in quality, 18.69% (SD 5.7) favoring auto-captured images and 36.51% (SD 9.0) preferring manually captured ones. Images with above average QS showed better agreement on segmentations (p < 0.001) and QS (p < 0.001) with fetal medicine experts. Auto-capture saved additional planes beyond protocol requirements, resulting in more comprehensive echocardiographies. Low QS had adverse effect on both model performance and clinician's agreement with model feedback. The findings highlight the importance of developing and evaluating AI models based on 'noisy' real-life data rather than pursuing the highest accuracy possible with retrospective academic-grade data.

Indexed as

EchocardiographyFemaleHumansPregnancyRetrospective Studies

Identifiers

PMID38461322
PMCPMC10925034

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.