Evidence map›Paper›PMID 38461275›Full record

ArticleTrials2024

Suicide prevention for substance using youth experiencing homelessness: study protocol for a randomized controlled trial.

Natasha Slesnick, Brittany Brakenhoff, Laura J Chavez, Caleb L Cuthbertson, Ruri Famelia, Xin Feng, Jodi Ford, Eugene Holowacz, Soren Jaderlund, Kelly Kelleher and 5 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05994612 (Suicide Prevention for Substance Using Youth Experiencing Homelessness), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05994612 narecruitingnot on this map

Suicide Prevention for Substance Using Youth Experiencing Homelessness

TypeinterventionalSponsorOhio State UniversityRan2023 to 2030Enrolled300ConditionsSuicide PreventionArmsCognitive Therapy for Suicide Prevention, Services as Usual
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Natasha SlesnickDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA. slesnick.5@osu.edu.ORCID http://orcid.org/0000-0002-6629-0333
Brittany BrakenhoffDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
Laura J ChavezCenter for Child Health Equity and Outcomes Research, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Caleb L CuthbertsonDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
Ruri FameliaDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
Xin FengDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
Jodi FordCollege of Nursing, The Ohio State University, 1577 Neil Ave, Columbus, OH, 43210, USA.
Eugene HolowaczDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
Soren JaderlundDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
Kelly KelleherCenter for Child Health Equity and Outcomes Research, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Ellison LuthyDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
Allen M MalloryDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
Alexis PizzuloDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
Tatiana D SlesnickCollege of Food, Agriculture and Environmental Science, School of Environment and National Resources, 2021 Fyffe Rd, Columbus, OH, 43210, USA.
Tansel YilmazerDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, 1787 Neil Ave, Columbus, OH, 43210, USA.
The Ohio State University · USNationwide Children's Hospital · US

Funding

Suicide Prevention with Substance Using Youth Experiencing HomelessnessR01DA058627 · NIDA · OHIO STATE UNIVERSITY · PI NATASHA SLESNICK · 2023 to 2026
$3.1M
NIDA NIH HHS R01 DA058627NIDA NIH HHS R01DA058627
6 · The paper itself

Abstract

backgroundWhile research on substance using youth experiencing homelessness (YEH) is increasing, there is a dearth of information regarding effective prevention interventions for these youth. Suicide is the leading cause of death among YEH and most youth do not access services that may be available to them. Therefore, this study seeks to address this gap in the research literature with the goal to identify an effective suicide prevention intervention that can be readily adopted by communities that serve these youth.

methodsThree hundred (N = 300) YEH with recent substance use and suicidal ideation or a recent suicide attempt will be recruited from the streets as well as a drop-in center serving YEH. After the baseline assessment, all youth will be randomly assigned to Cognitive Therapy for Suicide Prevention (CTSP) + Services as Usual (SAU) (N = 150) or to SAU alone (N = 150). SAU includes outreach, advocacy, and service linkage whereas YEH who receive CTSP will also receive ten CTSP sessions and an optional nine booster sessions. Follow-up assessments will be conducted at 3, 6, 9, and 12 months post-baseline. Theoretically derived mediators (e.g., cognitive distortions) will be tested to shed light on mechanisms associated with change, and the moderating effects of sex, race, sexual orientation, and baseline service connection will be examined. In order to ease future dissemination of the intervention to agencies serving YEH, we will rigorously assess acceptability, feasibility, fidelity, and cost associated with the delivery of our intervention approach using a mixed-methods approach. DISCUSSION: This study adds to a very small number of clinical trials seeking to prevent lethal suicide among a very high-risk group by addressing suicidal ideation directly rather than underlying conditions. It is hypothesized that youth receiving CTSP + SAU will show greater reductions in suicidal ideation (primary outcome), substance use, and depressive symptoms (secondary outcomes) over time compared to SAU alone, as well as improved risk and protective factors.

trial registrationNCT05994612. Date of Registration: August 16, 2023.

Indexed as

Ill-Housed PersonsSubstance-Related DisordersAdolescentFemaleHumansMaleRandomized Controlled Trials as TopicSuicidal IdeationSuicide, AttemptedSuicide PreventionRandomized controlled trialSubstance useSuicide preventionYouth homelessness

Identifiers

PMID38461275
PMCPMC10924986
OpenAlexW4392619311

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.