ArticleNature communications2024
Spatially selective delivery of living magnetic microrobots through torque-focusing.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- Task-Oriented Biomedical Microrobots: Access, Working Environment, Actuation, Body Design, Detection and Control.Micromachines · 2026Review
- Microrobots for Precision Diagnosis and Treatment in the Digestive System: A Review of Actuation Mechanisms, Structural Design, Preclinical and Translational Applications.Micromachines · 2026Review
- Hierarchically Engineered Magnetic-Enzymatic Microrobots with Stimuli-Induced Disassembly for Controlled Navigation and Mucosal Penetration in 3D Lung Fibrosis Models.Advanced healthcare materials · 2026Article
- Magnetic medical microrobots with memory-capable genetic circuits.Science advances · 2026Article
- Bacterial Biohybrids With Dual Magnet and Hypoxia Tropism for Ferroptosis Activation in Deep Tumor Regions.Exploration (Beijing, China) · 2026Article
- Targeting Cancers with Microrobots and Bacteriobots.Molecular biotechnology · 2026Review
- Image-based physical characterization of magnetotactic bacteria from an environmental sample.Microbiology spectrum · 2026Article
- Embodied Cross-Domain Intelligence in Biomedical Microrobots: A Review.Cyborg and bionic systems (Washington, D.C.) · 2026Review
- Navigating Cancer Treatment: A Journey from 2D to 3D Cancer Models and Nanoscale Therapies.ACS pharmacology & translational science · 2025Review
- Strategies for Navigating Magnetic Microrobots in Neurovascular Networks: A Numerical Analysis.Small science · 2025Article
- Technology Roadmap of Micro/Nanorobots.ACS nano · 2025Review
- Magnetite Micro/Nanorobots for Efficient Targeted Alleviation of Inflammatory Bowel Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Exploring the Complex Interplay of Anisotropies in Magnetosomes of Magnetotactic Bacteria.ACS omega · 2025Article
- Cilia-Mimic Locomotion of Magnetic Colloidal Collectives Enhanced by Low-Intensity Ultrasound for Thrombolytic Drug Penetration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Robotic Microcapsule Assemblies with Adaptive Mobility for Targeted Treatment of Rugged Biological Microenvironments.ACS nano · 2025Article
- Bacterial hitchhiking with drug-loaded nanoparticles as a drug delivery strategy for cancer immunotherapy.npj biomedical innovations · 2025Article
- Precision tumor treatment utilizing bacteria: principles and future perspectives.Applied microbiology and biotechnology · 2025Review
- Microrobotic Swarms for Cancer Therapy.Research (Washington, D.C.) · 2025Review
- Inductive sensing of magnetic microrobots under actuation by rotating magnetic fields.PNAS nexus · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rotating magnetic fields enable biomedical microrobots to overcome physiological barriers and promote extravasation and accumulation in tumors. Nevertheless, targeting deeply situated tumors requires suppression of off-target actuation in healthy tissue. Here, we investigate a control strategy for applying spatially selective torque density to microrobots by combining rotating fields with magnetostatic selection fields. Taking magnetotactic bacteria as diffuse torque-based actuators, we numerically model off-target torque suppression, indicating the feasibility of centimeter to millimeter resolution for human applications. We study focal torque application in vitro, observing off-target suppression of actuation-dependent effects such as colonization of bacteria in tumor spheroids. We then design and construct a mouse-scale torque-focusing apparatus capable of maneuvering the focal point. Applying this system to a mouse tumor model increased accumulation of intravenously injected bacteria within tumors receiving focused actuation compared to non-actuated or globally actuated groups. This control scheme combines the advantages of torque-based actuation with spatial targeting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.