Evidence map›Paper›PMID 38461237›Full record

ReviewCell communication and signaling : CCS2024

Strategies for labelling of exogenous and endogenous extracellular vesicles and their application for in vitro and in vivo functional studies.

Marie Boudna, Andres Delgado Campos, Petra Vychytilova-Faltejskova, Tana Machackova, Ondrej Slaby, Kamila Souckova

Open access · goldAbstract readReview
In one paragraph

Review in Cell communication and signaling : CCS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Natural Product-Derived Vesicles in Nanotherapeutics.Journal of extracellular vesicles · 2026
    Review
  3. TopicalPharmaceutics · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Journal of extracellular vesicles · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marie BoudnaCentral European Institute of Technology, Masaryk University, Kamenice 753/5, 625 00, Brno, Czech Republic.
Andres Delgado CamposCentral European Institute of Technology, Masaryk University, Kamenice 753/5, 625 00, Brno, Czech Republic.
Petra Vychytilova-FaltejskovaCentral European Institute of Technology, Masaryk University, Kamenice 753/5, 625 00, Brno, Czech Republic.
Tana MachackovaCentral European Institute of Technology, Masaryk University, Kamenice 753/5, 625 00, Brno, Czech Republic.
Ondrej SlabyCentral European Institute of Technology, Masaryk University, Kamenice 753/5, 625 00, Brno, Czech Republic. oslaby@med.muni.cz.
Kamila SouckovaCentral European Institute of Technology, Masaryk University, Kamenice 753/5, 625 00, Brno, Czech Republic. 11949@mail.muni.cz.
Central European Institute of Technology – Masaryk University · CZCentral European Institute of Technology · CZ

Funding

Grantová Agentura České Republiky 20-18889S
6 · The paper itself

Abstract

This review presents a comprehensive overview of labelling strategies for endogenous and exogenous extracellular vesicles, that can be utilised both in vitro and in vivo. It covers a broad spectrum of approaches, including fluorescent and bioluminescent labelling, and provides an analysis of their applications, strengths, and limitations. Furthermore, this article presents techniques that use radioactive tracers and contrast agents with the ability to track EVs both spatially and temporally. Emphasis is also placed on endogenous labelling mechanisms, represented by Cre-lox and CRISPR-Cas systems, which are powerful and flexible tools for real-time EV monitoring or tracking their fate in target cells. By summarizing the latest developments across these diverse labelling techniques, this review provides researchers with a reference to select the most appropriate labelling method for their EV based research.

Indexed as

Extracellular VesiclesBioluminescent labellingCre-loxPCRISPR-CasEV trackingExosomesExtracellular vesiclesFluorescent labellingIn vivo imagingMagnetic resonanceRadiolabelling

Identifiers

PMID38461237
PMCPMC10924393
OpenAlexW4392619589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.