Evidence map›Paper›PMID 38461234›Full record

ArticleBMC veterinary research2024

Attenuated vaccine PmCQ2Δ4555-4580 effectively protects mice against Pasteurella multocida infection.

Fang He, Pan Xiong, Huihui Zhang, Liu Yang, Yangyang Qiu, Pan Li, Guangfu Zhao, Nengzhang Li, Yuanyi Peng

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Advances inVaccines · 2025
    Review
  3. Article
  4. Article
  5. Exogenous L-Serine AlleviatesVeterinary sciences · 2025
    Article
  6. Evaluation of a multi-epitope vaccine PME forFrontiers in immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fang HeCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, China.
Pan XiongCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, China.
Huihui ZhangCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, China.
Liu YangCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, China.
Yangyang QiuCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, China.
Pan LiDepartment of Environment and Safety Engineering, Taiyuan institute of technology, Taiyuan, 030008, China.
Guangfu ZhaoCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, China.
Nengzhang LiCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, China. lich2001020@163.com.
Yuanyi PengCollege of Veterinary Medicine, Southwest University, Chongqing, 400715, China. pyy2002@sina.com.
Southwest University · CNTaiyuan Institute of Technology · CN

Funding

China Agriculture Research System of MOF and MARA (Beef/Yak Cattle, CARS-37)Fundamental Research Funds for the Central Universities (SWU-KQ22068)
6 · The paper itself

Abstract

Pasteurella multocida type A (PmA) mainly causes respiratory diseases such as pneumonia in bovines, leading to great economic losses to the breeding industry. At present, there is still no effective commercial vaccine against PmA infection. In this study, a mutant strain (PmCQ2Δ4555-4580) with brand-new phenotypes was obtained after serially passaging at 42 °C. Whole genome resequencing and PCR analysis showed that PmCQ2Δ4555-4580 missed six genes, including PmCQ2_004555, PmCQ2_004560, PmCQ2_004565, PmCQ2_004570, PmCQ2_004575, and PmCQ2_004580. Importantly, the virulence of PmCQ2Δ4555-4580 was reduced by approximately 2.8 × 10

Indexed as

Cattle DiseasesPasteurella InfectionsPasteurella multocidaRodent DiseasesAnimalsBacterial VaccinesCattleImmunizationMiceVaccinationVaccines, AttenuatedBacterial VaccinesVaccines, AttenuatedImmune protectionInfectionPasteurella multocidaVaccine

Identifiers

PMID38461234
PMCPMC10924365
OpenAlexW4392623411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.