Evidence map›Paper›PMID 38461216›Full record

ArticleCommunications biology2024

Transcranial direct current stimulation suggests a causal role of the medial prefrontal cortex in learning social hierarchy.

Chen Qu, Yulong Huang, Rémi Philippe, Shenggang Cai, Edmund Derrington, Frédéric Moisan, Mengke Shi, Jean-Claude Dreher

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Oxytocin modulates the neurocomputational mechanisms engaged in learning rank relationships in social networks.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Medial Frontal Theta Reduction Impairs Rule Switching via Prediction Error.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chen Qu *Center for Studies of Psychological Application, Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou, China.
Yulong Huang *Center for Studies of Psychological Application, Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou, China.ORCID 0000-0002-4155-9711
Rémi Philippe *Laboratory of Neuroeconomics, Institut des Sciences Cognitives Marc Jeannerod, CNRS, Lyon, France.ORCID 0000-0003-2894-7688
Shenggang CaiSchool of Economics and Management, South China Normal University, Guangzhou, China.
Edmund DerringtonLaboratory of Neuroeconomics, Institut des Sciences Cognitives Marc Jeannerod, CNRS, Lyon, France.
Frédéric MoisanGATE CNRS and EmLyon, Ecully, France.
Mengke ShiCenter for Studies of Psychological Application, Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou, China.
Jean-Claude DreherLaboratory of Neuroeconomics, Institut des Sciences Cognitives Marc Jeannerod, CNRS, Lyon, France. dreher@isc.cnrs.fr.ORCID 0000-0002-2157-1529

Funding

Agence Nationale de la Recherche (French National Research Agency) ADOSTRESS, ANR-21-CE37-0032-01Agence Nationale de la Recherche (French National Research Agency) ANR-11-IDEX-007Fondation de France FDF 00089590National Natural Science Foundation of China (National Science Foundation of China) 31970982National Natural Science Foundation of China (National Science Foundation of China) 32171019Université de Lyon (University of Lyon) IDEXLYON, ANR-16-IDEX-0005Université de Lyon (University of Lyon) LABEX CORTEX, ANR-11-LABX-0042
6 · The paper itself

Abstract

Social hierarchies can be inferred through observational learning of social relationships between individuals. Yet, little is known about the causal role of specific brain regions in learning hierarchies. Here, using transcranial direct current stimulation, we show a causal role of the medial prefrontal cortex (mPFC) in learning social versus non-social hierarchies. In a Training phase, participants acquired knowledge about social and non-social hierarchies by trial and error. During a Test phase, they were presented with two items from hierarchies that were never encountered together, requiring them to make transitive inferences. Anodal stimulation over mPFC impaired social compared with non-social hierarchy learning, and this modulation was influenced by the relative social rank of the members (higher or lower status). Anodal stimulation also impaired transitive inference making, but only during early blocks before learning was established. Together, these findings demonstrate a causal role of the mPFC in learning social ranks by observation.

Indexed as

Transcranial Direct Current StimulationBrainHierarchy, SocialHumansLearningPrefrontal Cortex

Identifiers

PMID38461216
PMCPMC10924847

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.