Evidence map›Paper›PMID 38461168›Full record

ArticleScientific reports2024

In vivo phenotypic vascular dysfunction extends beyond the aorta in a mouse model for fibrillin-1 (Fbn1) mutation.

T Curry, M E Barrameda, T Currier Thomas, M Esfandiarei

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Fibronectin-induced overactivation of αNature communications · 2026
    Article
  4. Integrin Signaling Pathways in Aortic Aneurysm and Dissection.Reviews in cardiovascular medicine · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

  • Update of
    2023
5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

T CurryCollege of Medicine-Phoenix, University of Arizona, Phoenix, AZ, USA.
M E BarramedaBiomedical Sciences Program, College of Graduate Studies, Midwestern University, 19555 N 59th Ave., Glendale, AZ, 85308, USA.
T Currier ThomasCollege of Medicine-Phoenix, University of Arizona, Phoenix, AZ, USA. theresathomas@arizona.edu.
M EsfandiareiCollege of Medicine-Phoenix, University of Arizona, Phoenix, AZ, USA. mesfan@midwestern.edu.
Midwestern University · USArizona Christian University · USBarrow Neurological Institute · US

Funding

Electrochemical assessment of behaviorally relevant circuit function after TBIR01NS100793 · NINDS · UNIVERSITY OF ARIZONA · PI THOMAS, THERESA CURRIER · 2018 to 2022
$1.7M
TARGETING ENDOTHELIAL DYSFUNCTION IN A GENETIC MOUSE MODEL OF AORTIC ANEURYSM: IMPLICATIONS FOR PREVENTION AND THERAPYR15HL145646 · NHLBI · MIDWESTERN UNIVERSITY · PI ESFANDIAREI, MITRA · 2019 to 2019
$441k
Accelerated Cerebrovascular Aging in a Fibrillin-1 Mutated Mouse ModelR36AG083385 · NIA · UNIVERSITY OF ARIZONA · PI CURRY-KOSKI, TALA · 2023 to 2024
$101k
NHLBI NIH HHS R15 HL145646NIA NIH HHS R36 AG083385NIH HHS R01NS100793NIH HHS R15HL145646NIH HHS R36AG083385NINDS NIH HHS R01 NS100793
6 · The paper itself

Abstract

In individuals with Marfan Syndrome (MFS), fibrillin-1 gene (FBN1) mutations can lead to vascular wall weakening and dysfunction. The experimental mouse model of MFS (Fbn1

Indexed as

AortaMarfan SyndromeAnimalsFemaleFibrillin-1MaleMiceMice, Inbred C57BLMutationPhenotypeFibrillin-1

Identifiers

PMID38461168
PMCPMC10924961
OpenAlexW4392620574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.