ArticleNature communications2024
Neural timescales reflect behavioral demands in freely moving rhesus macaques.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Behavioral engagement and stimulus regularities coordinate auditory-prefrontal network activity.PLoS biology · 2026Article
- Neural timescales from a computational perspective.Nature neuroscience · 2026Review
- Neuromorphic hierarchical modular reservoirs.Nature communications · 2026Article
- Temporal Structure of Reward Availability and Sensory Uncertainty Modulate Allocation Dynamics in Naturalistic Foraging.bioRxiv : the preprint server for biology · 2026Article
- Primate neuroethology: a new synthesis.Trends in cognitive sciences · 2026Review
- iSTTC: A robust method for accurate estimation of intrinsic neural timescales from single-unit recordings.PLoS computational biology · 2026Article
- Understanding the Brain as a Mentalizing Machine with a Symbol Grounding Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- Nested spatiotemporal theta-gamma waves organize hierarchical processing across the mouse visual cortex.Nature communications · 2026Article
- Temporal and Spatial Scales of Human Resting-State Cortical Activity across the Lifespan.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Infra-slow scale-free dynamics modulate the connection of neural and behavioral variability during attention.Communications biology · 2025Article
- Conserved brain-wide emergence of emotional response from sensory experience in humans and mice.Science (New York, N.Y.) · 2025Article
- Consistent Hierarchies of Single-Neuron Timescales in Mice, Macaques, and Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Sleep Modulates Neural Timescales and Spatiotemporal Integration in the Human Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Uncovering a Timescale Hierarchy by Studying the Brain in a Natural Context.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Network Mechanisms Underlying the Regional Diversity of Variance and Time Scales of the Brain's Spontaneous Activity Fluctuations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Ramping dynamics in the frontal cortex unfold over multiple timescales during motor planning.Journal of neurophysiology · 2025Article
- TiDHy: Timescale Demixing via Hypernetworks to learn simultaneous dynamics from mixed observations.bioRxiv : the preprint server for biology · 2025Article
- Flexibility of intrinsic neural timescales during distinct behavioral states.Communications biology · 2024Article
- Hierarchical gradients of multiple timescales in the mammalian forebrain.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Identification of movie encoding neurons enables movie recognition AI.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
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6 authors.
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Abstract
Previous work demonstrated a highly reproducible cortical hierarchy of neural timescales at rest, with sensory areas displaying fast, and higher-order association areas displaying slower timescales. The question arises how such stable hierarchies give rise to adaptive behavior that requires flexible adjustment of temporal coding and integration demands. Potentially, this lack of variability in the hierarchical organization of neural timescales could reflect the structure of the laboratory contexts. We posit that unconstrained paradigms are ideal to test whether the dynamics of neural timescales reflect behavioral demands. Here we measured timescales of local field potential activity while male rhesus macaques foraged in an open space. We found a hierarchy of neural timescales that differs from previous work. Importantly, although the magnitude of neural timescales expanded with task engagement, the brain areas' relative position in the hierarchy was stable. Next, we demonstrated that the change in neural timescales is dynamic and contains functionally-relevant information, differentiating between similar events in terms of motor demands and associated reward. Finally, we demonstrated that brain areas are differentially affected by these behavioral demands. These results demonstrate that while the space of neural timescales is anatomically constrained, the observed hierarchical organization and magnitude is dependent on behavioral demands.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.