Evidence map›Paper›PMID 38460318›Full record

Trial reportThe journal of nutrition, health & aging2024

The effect of lesser mealworm protein on exercise-induced muscle damage in active older adults: a randomized controlled trial.

Lotte Koopmans, Marcia Spoelder, Coen C W G Bongers, Thijs M H Eijsvogels, Maria T E Hopman

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The journal of nutrition, health & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Nutrition for healthy longevity: the past, the present and the future.The journal of nutrition, health & aging · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lotte KoopmansDepartment of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Marcia SpoelderDepartment of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Primary and Community Care, Radboud University Medical Center, Radboud, The Netherlands.
Coen C W G BongersDepartment of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands; School of Sport and Exercise, HAN University of Applied Sciences, Nijmegen, The Netherlands.
Thijs M H EijsvogelsDepartment of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Maria T E HopmanDepartment of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: maria.hopman@radboudumc.nl.
Radboud University Nijmegen · NLHAN University of Applied Sciences · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe compared the effect of 12 weeks lesser mealworm-based (Alphitobius diaperinus) protein supplementation to whey protein and placebo supplementation on Exercise-Induced Muscle Damage (EIMD) after long-distance walking in older adults.

methodsin this randomized controlled trial, 70 physically active older adults (>60 years) were randomly allocated to the following groups: I) lesser mealworm protein, II) whey protein or III) iso-caloric placebo. Participants received supplements 11 weeks before and 1 week during a 3-day long-distance walking challenge (30-50 km per day). Blood concentrations of creatinine kinase (CK) and lactate dehydrogenase (LDH), handgrip strength and muscle soreness were measured pre-exercise and directly after each walking bout.

resultsSignificant elevations of CK concentrations (103 [76-161] U/l to 758 [342-1104] U/l, p < 0.001) and LDH concentrations (202 [175-220] to 283 [252-339] U/l, p < 0.001) were observed following 7h45 min ± 11 min of walking exercise per day, but the magnitude of this effect did not differ among suppletion groups. Hand grip strength decreased significantly (p < 0.001) while muscle soreness increased (p = 0.002) after the first walking day compared to pre-exercise, with no group differences.

conclusion12-weeks of lesser mealworm-based protein supplementation (30 g/day) does not attenuate exercise induced muscle damage in older adults following three days of prolonged walking exercise in comparison to placebo or whey protein.

Indexed as

Creatine KinaseDietary SupplementsHand StrengthL-Lactate DehydrogenaseMuscle, SkeletalMyalgiaWalkingWhey ProteinsAgedAnimalsDietary ProteinsExerciseFemaleHelminth ProteinsHumansMaleCreatine KinaseDietary ProteinsHelminth ProteinsL-Lactate DehydrogenaseWhey ProteinsAlphitobius diaperinusElderlyEndurance exerciseInsectMuscle damage

Identifiers

PMID38460318
PMCPMC12877278
OpenAlexW4392611486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.