Evidence map›Paper›PMID 38460180›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Bioelectronic Direct Current Stimulation at the Transition Between Reversible and Irreversible Charge Transfer.

Lukas Matter, Oliya S Abdullaeva, Sebastian Shaner, José Leal, Maria Asplund

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. PEDOT:PSS-A Key Material for Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. 3D printing of micro-nano devices and their applications.Microsystems & nanoengineering · 2025
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lukas MatterDepartment of Microtechnology and Nanoscience, Chalmers University of Technology, Gothenburg, SE 41296, Sweden.ORCID 0009-0008-7723-5496
Oliya S AbdullaevaDivision of Nursing and Medical Technology, Luleå University of Technology, Luleå, SE 97187, Sweden.ORCID 0000-0002-0912-8305
Sebastian ShanerDepartment of Microsystems Engineering, University of Freiburg, Georges-Köhler-Allee 201, 79110, Freiburg, Germany.ORCID 0000-0001-8488-6803
José LealDepartment of Microsystems Engineering, University of Freiburg, Georges-Köhler-Allee 201, 79110, Freiburg, Germany.ORCID 0000-0003-3996-239X
Maria AsplundDepartment of Microtechnology and Nanoscience, Chalmers University of Technology, Gothenburg, SE 41296, Sweden.ORCID 0000-0001-8779-7478
University of Freiburg · DELuleå University of Technology · SE

Funding

European Research Council 101113487European Research Council 759655Health Research Council of New Zealand 19/895
6 · The paper itself

Abstract

Many biological processes rely on endogenous electric fields (EFs), including tissue regeneration, cell development, wound healing, and cancer metastasis. Mimicking these biological EFs by applying external direct current stimulation (DCS) is therefore the key to many new therapeutic strategies. During DCS, the charge transfer from electrode to tissue relies on a combination of reversible and irreversible electrochemical processes, which may generate toxic or bio-altering substances, including metal ions and reactive oxygen species (ROS). Poly(3,4-ethylenedioxythiophene) (PEDOT) based electrodes are emerging as suitable candidates for DCS to improve biocompatibility compared to metals. This work addresses whether PEDOT electrodes can be tailored to favor reversible biocompatible charge transfer. To this end, different PEDOT formulations and their respective back electrodes are studied using cyclic voltammetry, chronopotentiometry, and direct measurements of H

Indexed as

Bridged Bicyclo Compounds, HeterocyclicPolymersElectric StimulationElectrochemical TechniquesElectrodesHydrogen PeroxideReactive Oxygen SpeciesBridged Bicyclo Compounds, HeterocyclicHydrogen Peroxidepoly(3,4-ethylene dioxythiophene)PolymersReactive Oxygen Speciescapacitance estimationcharge transfer mechanismsdirect current electric fieldsreactive oxygen species

Identifiers

PMID38460180
PMCPMC11251568
OpenAlexW4392619215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.