Evidence map›Paper›PMID 38460166›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Biomimetic Self-Propelled Asymmetric Nanomotors for Cascade-Targeted Treatment of Neurological Inflammation.

Jiamin Ye, Yueyue Fan, Yaoguang She, Jiacheng Shi, Yiwen Yang, Xue Yuan, Ruiyan Li, Jingwen Han, Luntao Liu, Yong Kang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
25.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
  2. Imaging Study of MnOBiosensors · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  13. Cancer Neuroscience: Decoding Neural Circuitry in Tumor Evolution for Targeted Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  14. Review
  15. Article
  16. Micro/Nano-Motors for Enhanced Tumor Diagnosis and Therapy.International journal of molecular sciences · 2025
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jiamin YeAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Yueyue FanAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Yaoguang SheDepartment of General Surgery, the First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, 100853, China.
Jiacheng ShiAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Yiwen YangAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Xue YuanAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Ruiyan LiAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Jingwen HanAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Luntao LiuTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 100730, China.
Yong KangAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Xiaoyuan JiAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.ORCID 0000-0002-6768-2304
Tianjin University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNChinese PLA General Hospital · CNLinyi University · CN

Funding

National Natural Science Foundation of China 32071322National Outstanding Youth Science Fund Project of National Natural Science Foundation of China 32122044Technology & Innovation Commission of Shenzhen Municipality JCYJ20210324113004010
6 · The paper itself

Abstract

The precise targeted delivery of therapeutic agents to deep regions of the brain is crucial for the effective treatment of various neurological diseases. However, achieving this goal is challenging due to the presence of the blood‒brain barrier (BBB) and the complex anatomy of the brain. Here, a biomimetic self-propelled nanomotor with cascade targeting capacity is developed for the treatment of neurological inflammatory diseases. The self-propelled nanomotors are designed with biomimetic asymmetric structures with a mesoporous SiO

Indexed as

BiomimeticsBlood-Brain BarrierSilicon DioxideAnimalsBiomimetic MaterialsBrainCurcuminDisease Models, AnimalDrug Delivery SystemsInflammationMacrophagesManganese CompoundsMiceNanoparticlesNeuroinflammatory DiseasesOxidesCurcuminManganese CompoundsOxidesSilicon Dioxideanti‐inflammationasymmetricmacrophage polarizationnanomotornanozymeneurological inflammation

Identifiers

PMID38460166
PMCPMC11165487
OpenAlexW4392619171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.