Evidence map›Paper›PMID 38460127›Full record

ArticleExperimental physiology2024

The renal vasodilatation from β-adrenergic activation in vivo in rats is not driven by K

Charlotte Mehlin Sorensen, Max Salomonsson, Anniek Frederike Lubberding, Niels-Henrik Holstein-Rathlou

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Charlotte Mehlin SorensenDepartment of Biomedical Sciences, Physiology of Circulation, Kidney and Lung, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-9984-3125
Max SalomonssonTrelleborg Hospital, Trelleborg, Sweden.
Anniek Frederike LubberdingDepartment of Biomedical Sciences, Physiology of Inflammation, Metabolism and Oxidation, University of Copenhagen, Copenhagen, Denmark.
Niels-Henrik Holstein-RathlouDepartment of Biomedical Sciences, Physiology of Circulation, Kidney and Lung, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKTrelleborg (Sweden) · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms behind renal vasodilatation elicited by stimulation of β-adrenergic receptors are not clarified. As several classes of K channels are potentially activated, we tested the hypothesis that KV7 and BKCa channels contribute to the decreased renal vascular tone in vivo and in vitro. Changes in renal blood flow (RBF) during β-adrenergic stimulation were measured in anaesthetized rats using an ultrasonic flow probe. The isometric tension of segmental arteries from normo- and hypertensive rats and segmental arteries from wild-type mice and mice lacking functional K

Indexed as

KidneyVasodilationAdrenergic beta-AgonistsAnimalsHypertensionIsoproterenolKCNQ1 Potassium ChannelLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsMaleMiceMice, Inbred C57BLMice, KnockoutRatsRats, WistarReceptors, Adrenergic, betaRenal CirculationAdrenergic beta-AgonistsBKCa protein, mouseIsoproterenolKCNQ1 Potassium ChannelLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsReceptors, Adrenergic, betaK+ channelsKCNQrenal arteriesrenal vascular resistancesympathetic

Identifiers

PMID38460127
PMCPMC11061631
OpenAlexW4392619392

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.