Evidence map›Paper›PMID 38460060›Full record

ReviewHepatology international2024

Expert consensus on the diagnosis and treatment of end-stage liver disease complicated by infections.

Tao Chen, Guang Chen, Guiqiang Wang, Sombat Treeprasertsuk, Cosmas Rinaldi Adithya Lesmana, Han-Chieh Lin, Mamun Al-Mahtab, Yogesh K Chawla, Soek-Siam Tan, Jia-Horng Kao and 16 more

Open access · greenAbstract readConsensus StatementReview
PubMed Publisher
In one paragraph

Review in Hepatology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. [Risk Factors and Etiology of Pulmonary Fungal Infection in Patients With End-Stage Liver Disease].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
  9. Article
  10. Article
  11. [Abdominal organ transplantation in multimorbid patients].Chirurgie (Heidelberg, Germany) · 2025
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 20 institutions in 14 countries.

Tao ChenState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Department and Institute of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095, Jiefang Avenue, Wuhan, 430030, P.R. China.
Guang ChenState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Department and Institute of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095, Jiefang Avenue, Wuhan, 430030, P.R. China.
Guiqiang WangDepartment of Infectious Disease, Center for Liver Disease, Peking University First Hospital, Beijing, China.
Sombat TreeprasertsukDepartment of Medicine, Division of Gastroenterology, Faculty of Medicine, Chulalongkorn University, and Thai Red Cross, Bangkok, Thailand.
Cosmas Rinaldi Adithya LesmanaInternal Medicine, Hepatobiliary Division, Dr. Captor Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, DKI, Indonesia.
Han-Chieh LinFaculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Mamun Al-MahtabDepartment of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Yogesh K ChawlaDepartment of Gastroenterology and Hepatology, Kalinga Institute of Medical Sciences, Bhubaneswar, India.
Soek-Siam TanDepartment of Hepatology, Hospital Selayang, Selangor Darul Ehsan, Malaysia.
Jia-Horng KaoGraduate Institute of Clinical Medicine and Hepatitis Research Center, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan.
Man-Fung YuenDepartment of Medicine, School of Clinical Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
Guan-Huei LeeDivision of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore.
Diana Alcantara-PayawalFatima University Medical Center Manila, Manila, Philippines.
Nobuaki NakayamaDepartment of Gastroenterology & Hepatology, Saitama Medical University, Saitama, Japan.
Zaigham AbbasDepartment of Medicine, Ziauddin University Hospital, Karachi, Pakistan.
Wasim JafriDepartment of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Dong-Joon KimDepartment of Internal Medicine, Chuncheon Sacred Heart Hospital of Hallym University Medical Center, Chuncheon, Korea.
Ashok ChoudhuryDepartment of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
Rakhi MahiwallDepartment of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
Jinlin HouGuangdong Provincial Key Laboratory of Viral Hepatitis Research, Guangdong Provincial Clinical Research Center for Viral Hepatitis, Key Laboratory of Infectious Diseases Research in South China, Ministry of Education, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Saeed HamidDepartment of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Jidong JiaLiver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
J S BajajDepartment of Medicine, Virginia Commonwealth University and Central Virginia Veterans Healthcare System, Richmond, VA, USA.
Fusheng WangSenior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Shiv K SarinDepartment of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
Qin NingState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Department and Institute of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095, Jiefang Avenue, Wuhan, 430030, P.R. China. qning@vip.sina.com.ORCID http://orcid.org/0000-0002-2027-9593
Institute of Liver and Biliary Sciences · INTongji Hospital · CNAga Khan University Hospital · PKAll India Institute of Medical Sciences Bhubaneswar · INBangladesh Medical University · BDCapital Medical University · CNChinese PLA General Hospital · CNHallym University Chuncheon Sacred Heart Hospital · KRHospital Selayang · MYNanfang Hospital · CNNational Taiwan University Hospital · TWNational University Hospital · SGNational Yang Ming Chiao Tung University · TWOur Lady of Fatima University · PHPeking University · CNQueen Mary Hospital · CNSaitama Medical University · JPThai Red Cross Society · THUniversity of Indonesia · IDVirginia Commonwealth University · US

Funding

Key Technologies Research and Development Program 2021YFC2600200
6 · The paper itself

Abstract

End-stage liver disease (ESLD) is a life-threatening clinical syndrome and when complicated with infection the mortality is markedly increased. In patients with ESLD, bacterial or fungal infection can induce or aggravate the occurrence or progression of liver decompensation. Consequently, infections are among the most common complications of disease deterioration. There is an overwhelming need for standardized protocols for early diagnosis and appropriate management for patients with ESLD complicated by infections. Asia Pacific region has the largest number of ESLD patients, due to hepatitis B and the growing population of alcohol and NAFLD. Concomitant infections not only add to organ failure and high mortality but also to financial and healthcare burdens. This consensus document assembled up-to-date knowledge and experience from colleagues across the Asia-Pacific region, providing data on the principles as well as evidence-based current working protocols and practices for the diagnosis and treatment of patients with ESLD complicated by infections.

Indexed as

End Stage Liver DiseaseBacterial InfectionsHumansMycosesACLFAcute decompensationAntibioticsCirrhosisConsensusDecompensationInfectionOrgan failureSepsisSeptic shockTreatment

Identifiers

PMID38460060
OpenAlexW4392624996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.