Evidence map›Paper›PMID 38460014›Full record

Observational studyEuropean radiology2024

Prospective validation of the role of PET/CT in detecting disease after neoadjuvant chemotherapy in advanced ovarian cancer.

Elaine Yuen Phin Lee, Philip Pun Ching Ip, Ka Yu Tse, Keith Wan Hang Chiu, Mandy Man Yee Chu, Yu Ka Chai, Philip Yuguang Wu, Jessica Yun Pui Law, Shuk Tak Kwok, Wan Kam Chiu and 1 more

Open access · hybridAbstract readObservational StudyValidation Study
In one paragraph

Observational study in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Effect of neoadjuvant chemotherapy on [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Elaine Yuen Phin LeeDepartment of Diagnostic Radiology, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Room 406, Block K, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China. eyplee77@hku.hk.ORCID http://orcid.org/0000-0002-0627-5297
Philip Pun Ching IpDepartment of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Ka Yu TseDepartment of Obstetrics and Gynaecology, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Keith Wan Hang ChiuDepartment of Diagnostic Radiology, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Room 406, Block K, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China.
Mandy Man Yee ChuDepartment of Obstetrics and Gynaecology, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Yu Ka ChaiDepartment of Obstetrics and Gynaecology, United Christian Hospital, Hong Kong, China.
Philip Yuguang WuDepartment of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China.
Jessica Yun Pui LawDepartment of Obstetrics and Gynecology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China.
Shuk Tak KwokDepartment of Obstetrics and Gynaecology, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Wan Kam ChiuDepartment of Obstetrics and Gynaecology, United Christian Hospital, Hong Kong, China.
Hextan Yuen Sheung NganDepartment of Obstetrics and Gynaecology, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Chinese University of Hong Kong · HKPamela Youde Nethersole Eastern Hospital · CNQueen Mary Hospital · CNUnited Christian Hospital · CN

Funding

The Health and Medical Research Fund 06171706
6 · The paper itself

Abstract

objectivesThe study aimed to compare the diagnostic accuracies of 2-[ MATERIALS AND

methodsThis study consisted historical observational cohort and prospective validation cohort. Patients with newly diagnosed stage III-IV OC scheduled for NACT were recruited, with imaging performed after three to six cycles of NACT before interval debulking surgery. Nineteen regions in the abdominopelvic cavity were scored for the presence and absence of disease, referenced to the intra-operative findings or histological specimens. Diagnostic metrics were compared using McNemar's test.

resultsIn the historical cohort (23 patients, age 58 ± 13), 2-[

conclusion2-[ CLINICAL RELEVANCE STATEMENT: 2-[ KEY POINTS: • Additional value of 2-[

Indexed as

Fluorodeoxyglucose F18Neoadjuvant TherapyOvarian NeoplasmsPositron Emission Tomography Computed TomographyRadiopharmaceuticalsSensitivity and SpecificityAdultAgedContrast MediaFemaleHumansMiddle AgedProspective StudiesTomography, X-Ray ComputedContrast MediaFluorodeoxyglucose F18Radiopharmaceuticals2-[18F]FDG PET/CTChemotherapy response scoreContrast-enhanced CTNeoadjuvant chemotherapyOvarian cancer

Identifiers

PMID38460014
PMCPMC11364794
OpenAlexW4392619607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.