SynthesisArchives of gynecology and obstetrics2024
Global prevalence of major depressive disorder, generalized anxiety, stress, and depression among infertile women: a systematic review and meta-analysis.
Synthesis in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- The effect of expressive writing intervention for patients with reproductive trauma on anxiety, depression and stress: a meta-analysis of randomized controlled trials.BMC pregnancy and childbirth · 2026Pooled it
- Effects of emotions on IVF/ICSI outcomes in infertile women: a systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2025Pooled it
- Psilocibin: Current Evidence, Safety Signals, and Challenges in Assessing Potential Multi-Organ Effects.Biomedicines · 2026Review
- Sex-specific associations between psychological resilience and blastocyst quality.Reproduction & fertility · 2026Observational
- Psychosocial Aspects of Infertility and Medically Assisted Reproduction in Serbia: A COMPI-Based Single Centre Study.Healthcare (Basel, Switzerland) · 2026Article
- Network structure of depression and anxiety symptoms with psychosocial factors among Chinese women with primary infertility: a multi-center cross-sectional study.BMC psychiatry · 2026Article
- Maternal-fetal attachment trajectories in IVF mothers during the first trimester: a prospective observational study.Archives of gynecology and obstetrics · 2026Observational
- Evaluation of coping mechanisms and depression, anxiety, and stress in women with infertility: A cross-sectional study.International journal of reproductive biomedicine · 2026Article
- Endometrial cortisol level and its relationship with psychological stress, molecular tissue changes, and clinical outcomes in infertile women.Scientific reports · 2026Article
- A Study of Potential Classes and Trajectories of Psychological Distress in Infertility Patients: A Study Protocol.International journal of women's health · 2026Article
- Case Report: Right-sided vagus nerve stimulation for treatment-resistant affective disorders with complex cardiac comorbidity.Frontiers in psychiatry · 2026Article
- The Potential Relationship Between Low Back Pain and Depression: A Comprehensive Review.Brain and behavior · 2025Review
- Comparative analysis of hysterosalpingography and hysterosalpingo-contrast sonography for assessing tubal patency in women with endometriosis-related infertility: a propensity score-matched study.Archives of gynecology and obstetrics · 2025Article
- Psychopharmacological interventions among people who use Assisted Reproductive Technology (ART) - a scoping review.Reproductive biology and endocrinology : RB&E · 2025Article
- Silent battles, global insights: anxiety and depression in the world of assisted reproduction.Journal of assisted reproduction and genetics · 2025Review
- Psychological predictors, moderators, and mediators of treatment outcome among ART-treated women: a prospective study.Frontiers in reproductive health · 2025Article
- How Resilience Mitigates Depression After IVF-ET Failure: A Moderated Mediation Model of Hope, Social Relations, and Income in China.International journal of women's health · 2025Article
- Evaluation of the Effect of Jawarish Amla Concoction on Controlling Stress in Women Candidate Intracytoplasmic Sperm Injection orAdvanced biomedical research · 2025Article
- Is forest bathing a panacea for mental health problems? A narrative review.Frontiers in public health · 2025Review
- Exploring nursing care needs and the role of sleep quality in women undergoing infertility treatment: implications for personalized nursing interventions.Frontiers in public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent years, the global prevalence of infertility has increased among women (Talmor and Dunphy, Best Pract Res Clin Obstet Gynaecol 29(4):498-506, 2015) and is considered as a public health concern. One of the impacts of infertility is mental health problems in the patients, which can lead to complications such as stress, anxiety, and depression. The aim of this study is to investigate the global prevalence of major depressive disorder, general anxiety, stress, and depression in infertile women through a systematic review and meta-analysis.
methodsTo identify studies that have reported the prevalence of major depressive disorder, generalized anxiety, stress, and depression in infertile women, the PubMed, Scopus, Web of Science, Embase, ScienceDirect, and Google Scholar repositories were systematically searched. Articles published up until February 2023 were included, while no lower time limit was imposed in the search strategy. Heterogeneity of studies was examined using the I
resultsIn the review of 44 studies with a sample size of 53,300 infertile female patients, the overall prevalence of major depressive disorder (clinical depression), generalized anxiety, stress, and depression was found to be 22.9%, 13.3%, 78.8%, and 31.6% respectively. It was also found that mental health complications are more prevalent among infertile women in Asia (continent).
conclusionConsidering the prevalence of mental disorders among infertile women, health policymakers can use the results of the present meta-analysis to pay more attention to the mental health of infertile women and devise suitable interventions and programs to reduce and prevent the spread of psychological disorders among infertile women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.