Evidence map›Paper›PMID 38459772›Full record

ArticleThe Journal of infectious diseases2024

Incidence of Invasive and Noninvasive Pneumococcal Pneumonia Hospitalizations in People Aged ≥50 Years: Assessing Variability Across Denmark and Spain.

Mónica López-Lacort, Marzyeh Amini, Hanne-Dorthe Emborg, Jens Nielsen, Scott A McDonald, Palle Valentiner-Branth, Javier Díez-Domingo, Alejandro Orrico-Sánchez

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mónica López-LacortVaccine Research Department of Fisabio-Public Health, Valencia, Spain.
Marzyeh AminiP95 Epidemiology and Pharmacovigilance, Leuven, Belgium.
Hanne-Dorthe EmborgDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0001-8062-0864
Jens NielsenDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0001-6477-2219
Scott A McDonaldCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Amsterdam, The Netherlands.
Palle Valentiner-BranthDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.
Javier Díez-DomingoVaccine Research Department of Fisabio-Public Health, Valencia, Spain.
Alejandro Orrico-SánchezVaccine Research Department of Fisabio-Public Health, Valencia, Spain.ORCID 0000-0002-3780-3187

Funding

Dutch Ministry of Health, Welfare and SportEuropean Union's Horizon 2020 research innovation programInnovative Medicines Initiatives 2 Joint Undertaking 806776)
6 · The paper itself

Abstract

Determining pneumococcal pneumonia (PP) burden in the elderly population is challenging due to limited data on invasive PP (IPP) and, in particular, noninvasive PP (NIPP) incidence. Using retrospective cohorts of adults aged ≥50 years in Denmark (2 782 303) and the Valencia region, Spain (2 283 344), we found higher IPP hospitalization rates in Denmark than Valencia (18.3 vs 9/100 000 person-years [PY], respectively). Conversely, NIPP hospitalization rates were higher in Valencia (48.2 vs 7.2/100 000 PY). IPP and NIPP rates increased with age and comorbidities in both regions, with variations by sex and case characteristics (eg, complications, mortality). The burden of PP in adults is substantial, yet its true magnitude remains elusive. Discrepancies in clinical practices impede international comparisons; for instance, Valencia employed a higher frequency of urinary antigen tests compared to Denmark. Additionally, coding practices and prehospital antibiotic utilization may further influence these variations. These findings could guide policymakers and enhance the understanding of international disparities in disease burden assessments.

Indexed as

HospitalizationPneumonia, PneumococcalAgedAged, 80 and overAnti-Bacterial AgentsComorbidityDenmarkFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesSpainStreptococcus pneumoniaeAnti-Bacterial AgentsadultsepidemiologypneumococcuspneumoniaStreptococcus pneumoniae

Identifiers

PMID38459772
PMCPMC11420809

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.