Evidence map›Paper›PMID 38459600›Full record

SynthesisJournal of medical case reports2024

Primary extraskeletal intradural Ewing sarcoma with acute hemorrhage: a case report and review of the literature.

HusamEddin Salama, Lila H Abu-Hilal, Mayar Idkedek, Abdalwahab Kharousha, Mohand Abulihya, Hafez Nimer

Open access · goldAbstract readSystematic ReviewCase Reports
In one paragraph

Synthesis in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

HusamEddin SalamaMedical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Lila H Abu-HilalMedical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine. lila_abuhilal@yahoo.com.ORCID http://orcid.org/0000-0002-3754-0110
Mayar IdkedekMedical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Abdalwahab KharoushaDepartment of Neurosurgery, Al-Istishari Arab Hospital, Ramallah, West Bank, Palestine.
Mohand AbulihyaDepartment of Pathology, Al-Istishari Arab Hospital, Ramallah, West Bank, Palestine.
Hafez NimerDepartment of Neurosurgery, Al-Istishari Arab Hospital, Ramallah, West Bank, Palestine.
Al-Quds University · PSRafik Hariri University Hospital · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpinal cord tumors present a challenge in diagnosis and treatment due to their varied histopathological characteristics. While Ewing sarcoma is a rare malignant tumor typically originating from skeletal bone, cases of primary intradural extraskeletal Ewing sarcoma are exceptionally rare. The similarity of its presentation to other spinal tumors further complicates its identification and management. CASE PRESENTATION: We report a case of a 58-year-old Palestinian male with intradural extraskeletal lumbar Ewing sarcoma. The patient initially presented with lower back pain and bilateral S1 radiculopathy, with more severe symptoms on the left side. Magnetic resonance imaging revealed a 7 cm oval-shaped mass with homogeneous contrast enhancement, obstructing the spinal canal from L3/L4 to L5/S1 levels. Initially, a myxopapillary ependymoma was suspected, but the patient's sensory and motor functions suddenly deteriorated during hospitalization. Repeat magnetic resonance imaging indicated heterogeneous contrast enhancement, indicating acute intratumoral hemorrhage. Consequently, the patient underwent emergent L3-L5 laminotomy, with successful gross total resection of the tumor. Histopathological and immunohistochemical analyses confirmed the diagnosis of intradural extraskeletal Ewing sarcoma. Adjuvant therapy was administered to minimize the risk of local recurrence or distant metastasis. A systematic review of relevant literature, along with retrospective analysis of medical records, operative reports, radiological studies, and histopathological findings of similar cases, was also conducted.

conclusionsIntradural extraskeletal Ewing sarcoma is an infrequently encountered condition in adult patients, emphasizing the importance of considering it in the differential diagnosis of spinal tumors. Surgeons must possess a comprehensive understanding of this rare entity to ensure accurate staging and optimal management, particularly in the early stages when prompt intervention may improve prognosis.

Indexed as

Sarcoma, EwingSpinal Cord NeoplasmsSpinal NeoplasmsHumansMaleMiddle AgedPrognosisChemotherapyEwing sarcomaExtra-skeletalIntraduralIntratumoral hemorrhageRadiotherapyTumor

Identifiers

PMID38459600
PMCPMC10924417
OpenAlexW4392639363

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.