Evidence map›Paper›PMID 38459510›Full record

Trial reportBMC pediatrics2024

Health-related quality of life and self-reported health status in adolescents with chronic health conditions before transfer of care to adult health care: an international cohort study.

Mira Kallio, Anna Tornivuori, Päivi J Miettinen, Kaija-Leena Kolho, Heikki Relas, Evelyn Culnane, Hayley Loftus, Susan M Sawyer, Silja Kosola

Registry-linked trialAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04631965 (Bridge), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04631965 unknown statusnot on this map

Bridge: an International Longitudinal Study of Healthcare Transition of Adolescents With Severe Chronic Health Conditions

TypeobservationalSponsorUniversity of HelsinkiRan2017 to 2023Enrolled503ConditionsTransition, Diabetes, Kidney Diseases, Liver DiseasesArmsTransition support service
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mira KallioDepartment of Pediatrics, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. mira.kallio@hus.fi.
Anna TornivuoriDepartment of Nursing Science, University of Turku, Turku, Finland.
Päivi J MiettinenDepartment of Pediatrics, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Kaija-Leena KolhoDepartment of Pediatrics, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Heikki RelasDepartment of Rheumatology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Evelyn CulnaneTransition Support Service, The Royal Children's Hospital, Melbourne, Australia.
Hayley LoftusTransition Support Service, The Royal Children's Hospital, Melbourne, Australia.
Susan M SawyerCentre for Adolescent Health, Royal Children's Hospital, Melbourne, Australia.
Silja KosolaDepartment of Pediatrics, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeath-related quality of life (HRQoL) is lower in adolescents with chronic health conditions compared to healthy peers. While there is evidence of some differences according to the underlying condition and gender, differences by measure and country are poorly understood. In this study we focus on the differences in HRQoL in adolescents with various chronic medical conditions in the year before transfer of care to adult health services. We also study the associations of two different HRQoL measurements to each other and to self-reported health.

methodsWe recruited 538 adolescents from New Children`s Hospital, Helsinki, Finland, and the Royal Children`s Hospital, Melbourne, Australia in 2017-2020. We used two validated HRQoL measurement instruments, Pediatric Quality of Life Inventory (PedsQL) and 16D, and a visual analog scale (VAS) for self-reported health status.

resultsIn total, 512 adolescents (50.4% female, mean age 17.8 [SD 1.2] years), completed the survey measures. Higher HRQoL was reported in males than females in both countries (PedsQL 79.4 vs. 74.1; 16D 0.888 vs. 0.846), and in adolescents from Finland than Australia (80.6 vs. 72.2 and 0.905 vs. 0.825, p < 0.001 for all). Adolescents with diabetes, rheumatological, nephrological conditions and/or organ transplants had higher HRQoL than adolescents with neurological conditions or other disease syndromes (p < 0.001). PedsQL and 16D scores showed a strong correlation to each other (Spearman correlation coefficient r = 0.81). Using the 7-point VAS (1-7), 52% (248 of 479) considered their health status to be good (6-7) and 10% (48 of 479) rated it poor (1-2). Better self-reported health was associated with higher HRQoL.

conclusionsThe HRQoL of transition aged adolescents varies between genders, diagnostic groups, and countries of residence. The association between self-reported health and HRQoL suggests that brief assessment using the VAS could identify adolescents who may benefit from in-depth HRQoL evaluation.

trial registrationTrial registration name The Bridge and registration number NCT04631965 ( https://clinicaltrials.gov/ct2/show/NCT04631965 ).

Indexed as

Health StatusQuality of LifeAdolescentAdultAgedChildChronic DiseaseCohort StudiesDelivery of Health CareFemaleHumansMaleSelf ReportSurveys and Questionnaires16DAdolescentsChronic medical conditionsHealth-related quality of lifePedsQLSelf-reported healthTransfer of careTransition

Identifiers

PMID38459510
PMCPMC10921592

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.