Evidence map›Paper›PMID 38459495›Full record

ArticleBMC geriatrics2024

Feasibility and usefulness of cognitive monitoring using a new home-based cognitive test in mild cognitive impairment: a prospective single arm study.

Kyung Won Lee, Yun Jeong Hong, Eun Jin Yang, Si Baek Lee, Seong Hoon Kim, Seunghee Na, Young-Do Kim, Jeong Wook Park

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kyung Won LeeDepartment of Neurology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, 11765, Seoul, Korea.
Yun Jeong HongDepartment of Neurology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, 11765, Seoul, Korea. hyj2009@hanmail.net.
Eun Jin YangDepartment of Neurology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, 11765, Seoul, Korea.
Si Baek LeeDepartment of Neurology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, 11765, Seoul, Korea.
Seong Hoon KimDepartment of Neurology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, 11765, Seoul, Korea.
Seunghee NaDepartment of Neurology, Incheon St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Young-Do KimDepartment of Neurology, Incheon St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Jeong Wook ParkDepartment of Neurology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, 11765, Seoul, Korea.
Catholic University of Korea · KRThe Catholic University of Korea Uijeongbu St. Mary's Hospital · KR

Funding

National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) 2020R1C1C1006121the Catholic University of Korea Uijeongbu St. Mary's Hospital Clinical Research Laboratory Foundation in the program year of 2019, 2020.
6 · The paper itself

Abstract

backgroundThe risk of dementia is increased in subjects with mild cognitive impairment (MCI). Despite the plethora of in-person cognitive tests, those that can be administered over the phone are lacking. We hypothesized that a home-based cognitive test (HCT) using phone calls would be feasible and useful in non-demented elderly. We aimed to assess feasibility and validity of a new HCT as an optional cognitive monitoring tool without visiting hospitals.

methodsOur study was conducted in a prospective design during 24 weeks. We developed a new HCT consisting of 20 questions (score range 0-30). Participants with MCI (n = 38) were consecutively enrolled and underwent regular HCTs during 24 weeks. Associations between HCT scores and in-person cognitive scores and Alzheimer's disease (AD) biomarkers were evaluated. In addition, HCT scores in MCI participants were cross-sectionally compared with age-matched cognitively normal (n = 30) and mild AD dementia (n = 17) participants for discriminative ability of the HCT.

resultsHCT had good intra-class reliability (test-retest Cronbach's alpha 0.839). HCT scores were correlated with the Mini-Mental State Examination (MMSE), verbal memory delayed recall, and Stroop test scores but not associated with AD biomarkers. HCT scores significantly differed among cognitively normal, MCI, and mild dementia participants, indicating its discriminative ability. Finally, 32 MCI participants completed follow-up evaluations, and 8 progressed to dementia. Baseline HCT scores in dementia progressors were lower than those in non-progressors (p = 0.001).

conclusionThe feasibility and usefulness of the HCT were demonstrated in elderly subjects with MCI. HCT could be an alternative option to monitor cognitive decline in early stages without dementia.

Indexed as

Alzheimer DiseaseCognitive DysfunctionDementiaAgedBiomarkersCognitionFeasibility StudiesHumansNeuropsychological TestsReproducibility of ResultsBiomarkersAlzheimer’s diseaseCognitive monitoringMild cognitive impairmentTelephone-based cognitive testValidation

Identifiers

PMID38459495
PMCPMC10924318
OpenAlexW4392585850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.