SynthesisBMC neurology2024
A systematic review and meta-analysis of clinical efficacy of early and late rehabilitation interventions for ischemic stroke.
Synthesis in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Rehabilitation for degenerative cervical myelopathy: systematic review and scoping review of UK patient information.Spinal cord · 2025Pooled it
- Effects of very early exercise on inflammatory markers and clinical outcomes in patients with ischaemic stroke- a randomized controlled trial.BMC neurology · 2025Trial
- Post-stroke rehabilitative mechanisms in individualized fatigue level-controlled treadmill training in rats.Neural regeneration research · 2026Article
- Neurological sequelae of massive bee envenomation: a rare case report of watershed cerebral infarction and hemorrhage.Annals of medicine and surgery (2012) · 2026Article
- Cortical neuromodulation by vibration-induced illusion of movement is observed in older individuals, but not in individuals with acute stroke: a cross-sectional fNIRS study.Journal of neuroengineering and rehabilitation · 2026Article
- A latent transition analysis of longitudinal stability of post-stroke fatigue.Social psychiatry and psychiatric epidemiology · 2026Article
- Survival, Recorded Disability, and Neurorehabilitation After Advanced Endovascular Stroke Care in Kazakhstan: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Benefits and Importance of Early Rehabilitation in Patients After Stroke.Journal of functional morphology and kinesiology · 2026Review
- A scoping review of outcome and outcome measure sets for adults with spinal cord injury, stroke, and traumatic brain injury.Journal of rehabilitation medicine · 2026Article
- Rehabilitation utilisation up to 24 months after stroke: a register-based cohort study in southern Sweden.European stroke journal · 2026Article
- Electronic Medical Record Data-Based Analysis of Discharge Pathways and Functional Recovery by Surgical Procedure Among Patients with Hip-Related Fractures in a Convalescent Rehabilitation Hospital: A Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Long-Term Outcome After Intensive Stroke Rehabilitation.Journal of clinical medicine · 2026Article
- Efficacy of goal-directed rehabilitation on functional recovery in patients with cerebral infarction.Medicine · 2026Article
- Level of disability and associated factors among stroke survivors in Ethiopia: a multicenter cross-sectional study.BMC public health · 2026Article
- Early Predictors of Long-Term Outcome in Basilar Artery Occlusion: A Post Hoc Analysis of the ATTENTION Trial.Journal of stroke · 2026Article
- Effects of evidence-based early mobilization on prognostic outcomes in older patients with acute ischemic stroke.Frontiers in public health · 2026Article
- Nurses as guardians of time: the hidden clinical value of continuous care in geriatrics.Frontiers in public health · 2026Review
- Efficacy of Early Mobilization in Stroke Patients in Relation to Quality of Life and Level of Dependency: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Stroke-related parameters affecting the deterioration of oral health-related quality of life as measured by OHIP-14 three months after ischemic stroke.BMC oral health · 2025Article
- Effectiveness of evidence-based nursing on functional outcomes in patients with ischemic stroke: A retrospective cohort study.Medicine · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAt present, stroke has become the first cause of death and disability among Chinese adults. With the coming of the aging population in China, the disease burden brought by stroke will be increasingly aggravated. And stroke is a leading cause of disability. There is a golden plastic period after stroke, during which timely and safe intervention and rehabilitation therapy can effectively improve the disability status. However, there is still controversy about the duration of interventional rehabilitation after stroke. This study conducted a meta-analysis on the influence of intervention in early and late ischemic stroke rehabilitation.
methodChinese language databases such as CNKI, Wanfang, and VIP, and English language databases such as Embase, PubMed, Web of Science, and The Cochrane Library were searched, and RCT related to early and late rehabilitation of ischemic stroke from the establishment of the database to October 2023 was collected. Review Manager 5.4.1 was used for relevant analysis. The main outcomes were Barthel Index or Modified Barthel Index, Fugl-Meyer Assessment scale, NIHSS, China Stroke Scale. Standardized Mean Difference (SMD) was used as an effective indicator of continuity variables, and the estimated interval was expressed by 95% confidence interval (CI).
resultsA total of 1908 patients were included in 16 studies. The results showed that, compared with late rehabilitation, early rehabilitation improved clinical efficacy. Barthel Index or Modified Barthel Index score was [SMD = 1.40, 95%CI(1.16,1.63), p < 0.001]; the score of Fugl-Meyer Assessment Scale was [SMD = 1.18, 95%Cl (0.85, 1.52), P < 0.001]; the score of NIHSS was [SMD= -0.44, 95% CI(-0.65, -0.24), P < 0.001]; the result of China Stroke Scale score was [SMD= -0.37, 95%CI(-0.56, -0.18), P < 0.001].
conclusionIn comparison with late rehabilitation, early rehabilitation can significantly improve self-care abilities, daily activities, and neurological functions of ischemic stroke patients.
trial registrationThis meta-analysis has been registered with Prospero, and the registration number is CRD42022309911. The registration period is March 22, 2022.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.