Evidence map›Paper›PMID 38459362›Full record

ArticleClinical oral investigations2024

Performance of a commercially available Generative Pre-trained Transformer (GPT) in describing radiolucent lesions in panoramic radiographs and establishing differential diagnoses.

Thaísa Pinheiro Silva, Maria Fernanda Silva Andrade-Bortoletto, Thaís Santos Cerqueira Ocampo, Caio Alencar-Palha, Michael M Bornstein, Christiano Oliveira-Santos, Matheus L Oliveira

Abstract read
In one paragraph

Article in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Transformer-based models in dentistry: a systematic review.BMC medical informatics and decision making · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thaísa Pinheiro SilvaDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas, Piracicaba, Sao Paulo, 13414-903, Brazil.ORCID http://orcid.org/0000-0002-7485-0206
Maria Fernanda Silva Andrade-BortolettoDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas, Piracicaba, Sao Paulo, 13414-903, Brazil.ORCID http://orcid.org/0000-0003-2300-3143
Thaís Santos Cerqueira OcampoDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas, Piracicaba, Sao Paulo, 13414-903, Brazil.ORCID http://orcid.org/0000-0002-6913-4416
Caio Alencar-PalhaDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas, Piracicaba, Sao Paulo, 13414-903, Brazil.ORCID http://orcid.org/0000-0003-1856-793X
Michael M BornsteinDepartment of Oral Health & Medicine, University Center for Dental Medicine Basel UZB, University of Basel, Basel, 4058, Switzerland.ORCID http://orcid.org/0000-0002-7773-8957
Christiano Oliveira-SantosDepartment of Diagnosis and Oral Health, University of Louisville School of Dentistry, Louisville, KY, 40202, USA.ORCID http://orcid.org/0000-0001-9936-7547
Matheus L OliveiraDepartment of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas, Piracicaba, Sao Paulo, 13414-903, Brazil. matheus.limadeoliveira@unibas.ch.ORCID http://orcid.org/0000-0002-8054-8759

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the performance of a commercially available Generative Pre-trained Transformer (GPT) in describing and establishing differential diagnoses for radiolucent lesions in panoramic radiographs. MATERIALS AND

methodsTwenty-eight panoramic radiographs, each containing a single radiolucent lesion, were evaluated in consensus by three examiners and a commercially available ChatGPT-3.5 model. They provided descriptions regarding internal structure (radiodensity, loculation), periphery (margin type, cortication), shape, location (bone, side, region, teeth/structures), and effects on adjacent structures (effect, adjacent structure). Diagnostic impressions related to origin, behavior, and nature were also provided. The GPT program was additionally prompted to provide differential diagnoses. Keywords used by the GPT program were compared to those used by the examiners and scored as 0 (incorrect), 0.5 (partially correct), or 1 (correct). Mean score values and standard deviation were calculated for each description. Performance in establishing differential diagnoses was assessed using Rank-1, -2, and - 3.

resultsDescriptions of margination, affected bone, and origin received the highest scores: 0.93, 0.93, and 0.87, respectively. Shape, region, teeth/structures, effect, affected region, and nature received considerably lower scores ranging from 0.22 to 0.50. Rank-1, -2, and - 3 demonstrated accuracy in 25%, 57.14%, and 67.85% of cases, respectively.

conclusionThe performance of the GPT program in describing and providing differential diagnoses for radiolucent lesions in panoramic radiographs is variable and at this stage limited in its use for clinical application. CLINICAL RELEVANCE: Understanding the potential role of GPT systems as an auxiliary tool in image interpretation is imperative to validate their clinical applicability.

Indexed as

Diagnosis, DifferentialConsensusRadiography, PanoramicArtificial intelligenceDifferential diagnosisGenerative pre-trained transformerPanoramic radiography

Identifiers

PMID38459362
PMCPMC10924032

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.