Evidence map›Paper›PMID 38459100›Full record

ArticleScientific reports2024

AtPCa-Net: anatomical-aware prostate cancer detection network on multi-parametric MRI.

Haoxin Zheng, Alex Ling Yu Hung, Qi Miao, Weinan Song, Fabien Scalzo, Steven S Raman, Kai Zhao, Kyunghyun Sung

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Cross-Slice Attention and Evidential Critical Loss for Uncertainty-Aware Prostate Cancer Detection.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Haoxin ZhengRadiological Sciences, University of California, Los Angeles, Los Angeles, 90095, USA. haoxinzheng@g.ucla.edu.
Alex Ling Yu HungRadiological Sciences, University of California, Los Angeles, Los Angeles, 90095, USA.
Qi MiaoRadiological Sciences, University of California, Los Angeles, Los Angeles, 90095, USA.
Weinan SongElectrical and Computer Engineering, University of California, Los Angeles, Los Angeles, 90095, USA.
Fabien ScalzoComputer Science, University of California, Los Angeles, Los Angeles, 90095, USA.
Steven S RamanRadiological Sciences, University of California, Los Angeles, Los Angeles, 90095, USA.
Kai ZhaoRadiological Sciences, University of California, Los Angeles, Los Angeles, 90095, USA.
Kyunghyun SungRadiological Sciences, University of California, Los Angeles, Los Angeles, 90095, USA.
University of California, Los Angeles · US

Funding

Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer ClassificationR01CA248506 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUNG, KYUNG HYUN, WU, HOLDEN H · 2020 to 2024
$3.0M
Racially-associated MRI analysis and modeling for predicting aggressive prostate cancerR01CA272702 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Harrison Kim, Kyung Hyun Sung · 2023 to 2026
$2.4M
NCI NIH HHS R01 CA248506NCI NIH HHS R01 CA272702NIH HHS R01-CA248506
6 · The paper itself

Abstract

Multi-parametric MRI (mpMRI) is widely used for prostate cancer (PCa) diagnosis. Deep learning models show good performance in detecting PCa on mpMRI, but domain-specific PCa-related anatomical information is sometimes overlooked and not fully explored even by state-of-the-art deep learning models, causing potential suboptimal performances in PCa detection. Symmetric-related anatomical information is commonly used when distinguishing PCa lesions from other visually similar but benign prostate tissue. In addition, different combinations of mpMRI findings are used for evaluating the aggressiveness of PCa for abnormal findings allocated in different prostate zones. In this study, we investigate these domain-specific anatomical properties in PCa diagnosis and how we can adopt them into the deep learning framework to improve the model's detection performance. We propose an anatomical-aware PCa detection Network (AtPCa-Net) for PCa detection on mpMRI. Experiments show that the AtPCa-Net can better utilize the anatomical-related information, and the proposed anatomical-aware designs help improve the overall model performance on both PCa detection and patient-level classification.

Indexed as

Multiparametric Magnetic Resonance ImagingProstatic NeoplasmsHumansImage-Guided BiopsyMagnetic Resonance ImagingMaleProstate

Identifiers

PMID38459100
PMCPMC10923873
OpenAlexW4392597573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.