Evidence map›Paper›PMID 38457918›Full record

ReviewEFORT open reviews2024

Synovial sarcoma: the misdiagnosed sarcoma.

Chengxiang Li, Fatime Krasniqi, Ricardo Donners, Christoph Kettelhack, Andreas H Krieg

Open access · goldAbstract readReview
In one paragraph

Review in EFORT open reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Diagnostic challenges in synovial sarcoma: a case report.Journal of medical case reports · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Histology-Tailored Approach to Soft Tissue Sarcoma.Annals of surgical oncology · 2024
    Review
  10. Combination of HDAC and FYN inhibitors in synovial sarcoma treatment.Frontiers in cell and developmental biology · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chengxiang LiDepartment of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland.ORCID 0000-0002-6981-3128
Fatime KrasniqiDepartment of Oncology, University Hospital Basel, Basel, Switzerland.
Ricardo DonnersThe Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland.
Christoph KettelhackThe Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland.
Andreas H KriegDepartment of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland.ORCID 0000-0001-6008-5657
University of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synovial sarcoma is a rare and highly malignant soft tissue sarcoma. The inconspicuous and diversity of its early symptoms make it a highly misdiagnosed disease. The management of synovial sarcomas is challenging as they are rare and have a poor prognosis. Early and correct diagnosis and treatment are critical for clinical outcomes. Misdiagnosis or delayed diagnosis can have devastating consequences for the patient. The detection of SS18 gene rearrangement is considered a powerful tool in establishing the diagnosis of synovial sarcomas. Biopsies and testing for gene rearrangements are recommended for all patients in whom SS cannot be excluded. Surgery is the mainstay of treatment for synovial sarcomas. Neoadjuvant/adjuvant radiotherapy is recommended for patients with big tumors (>5 cm) or positive resection margins, and neoadjuvant/adjuvant chemotherapy is recommended for patients with high-risk tumors or advanced diseases. This article reviews synovial sarcomas from the perspectives of clinical and radiological presentation, histological and cytogenetic analysis, differential diagnosis, treatment, and prognosis.

Indexed as

malignantmisdiagnosedsarcomasynovial sarcoma

Identifiers

PMID38457918
PMCPMC10958242
OpenAlexW4392459280

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.