Evidence map›Paper›PMID 38457907›Full record

ArticleCell calcium2024

Neighbourhood Watch: Two-pore-2 channels talking to IP3 receptors.

David N Criddle, Alexei V Tepikin

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell calcium, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David N CriddleDepartment of Molecular & Clinical Cancer Medicine, Institute of Systems, Molecular & Integrative Biology, Crown Street, University of Liverpool, Liverpool L69 3BX, United Kingdom. Electronic address: criddle@liverpool.ac.uk.
Alexei V TepikinDepartment of Molecular & Clinical Cancer Medicine, Institute of Systems, Molecular & Integrative Biology, Crown Street, University of Liverpool, Liverpool L69 3BX, United Kingdom. Electronic address: a.tepikin@liverpool.ac.uk.
University of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent elegant study by Y. Yuan and colleagues examined functional relationships between the lysosomal two-pore channels 2 (TPC2) and IP3 receptors (IP3Rs) located in the endoplasmic reticulum [1]. The findings of this study suggest functional coupling of these channels and receptors. The study also describes interesting novel phenomena, which may indicate an additional coupling mechanism.

Indexed as

Calcium SignalingTwo-Pore ChannelsCalciumEndoplasmic ReticulumInositol 1,4,5-Trisphosphate ReceptorsLysosomesNADPCalciumInositol 1,4,5-Trisphosphate ReceptorsNADPTwo-Pore ChannelsCa2+IP3 receptorsNAADPTPC2-A1-NTwo-pore channels

Identifiers

PMID38457907
OpenAlexW4392626886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.