Evidence map›Paper›PMID 38457521›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Rapid dissemination of host metabolism-manipulating genes via integrative and conjugative elements.

Elena Colombi, Frederic Bertels, Guilhem Doulcier, Ellen McConnell, Tatyana Pichugina, Kee Hoon Sohn, Christina Straub, Honour C McCann, Paul B Rainey

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
10.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Horizontal transfer of ICEJournal of bacteriology · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Jumbo phage-mediated transduction of genomic islands.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
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  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 5 countries.

Elena ColombiSchool of Agriculture, Food and Ecosystem Sciences, Faculty of Science, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-3753-4925
Frederic BertelsDepartment of Microbial Population Biology, Max Planck Institute for Evolutionary Biology, Plön 24306, Germany.ORCID 0000-0001-6222-4139
Guilhem DoulcierLaboratoire Biophysique et Évolution, Institut Chemie Biologie Innovation, École Supérieure de Physique et de Chemie Industrielles de la Ville de Paris, Université Paris Science et Lettres, Centre National de al Reserche Scientifique, Paris 75005, France.
Ellen McConnellDepartment of Microbial Population Biology, Max Planck Institute for Evolutionary Biology, Plön 24306, Germany.ORCID 0009-0004-2284-9213
Tatyana PichuginaDepartment of Microbial Population Biology, Max Planck Institute for Evolutionary Biology, Plön 24306, Germany.ORCID 0009-0005-7741-8389
Kee Hoon SohnPlant Immunity Research Center, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-9021-8649
Christina StraubHealth and Environment, Institute of Environmental Science and Research, Auckland 1025, New Zealand.ORCID 0000-0002-1047-1362
Honour C McCannPlant Pathogen Evolution Research Group, Max Planck Institute for Biology, Tübingen 72076, Germany.
Paul B RaineyDepartment of Microbial Population Biology, Max Planck Institute for Evolutionary Biology, Plön 24306, Germany.ORCID 0000-0003-0879-5795
Max Planck Institute for Evolutionary Biology · DEMax Planck Institute for Biology · DESeoul National University · KRThe University of Melbourne · AUUniversity of Vienna · AT

Funding

Deutsche Forschungsgemeinschaft (DFG) SFB1182 Project C4Royal Society of New Zealand | Marsden Fund (Royal Society of New Zealand Marsden Fund) MAU1709
6 · The paper itself

Abstract

Integrative and conjugative elements (ICEs) are self-transmissible mobile elements that transfer functional genetic units across broad phylogenetic distances. Accessory genes shuttled by ICEs can make significant contributions to bacterial fitness. Most ICEs characterized to date encode readily observable phenotypes contributing to symbiosis, pathogenicity, and antimicrobial resistance, yet the majority of ICEs carry genes of unknown function. Recent observations of rapid acquisition of ICEs in a pandemic lineage of

Indexed as

Conjugation, GeneticGene Transfer, HorizontalBiological EvolutionDNA Transposable ElementsPhylogenyDNA Transposable Elementshorizontal gene transfermicrobial evolutionmobile elementsplant–microbe interactions

Identifiers

PMID38457521
PMCPMC10945833
OpenAlexW4392581511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.