Evidence map›Paper›PMID 38457506›Full record

ArticleScience advances2024

Quantum imaging of biological organisms through spatial and polarization entanglement.

Yide Zhang, Zhe He, Xin Tong, David C Garrett, Rui Cao, Lihong V Wang

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Quantum-enhanced coherent Raman spectroscopy with broadband squeezed-light detection.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Application of quantum imaging in biology.Biomedical optics express · 2025
    Review
  14. Review
  15. Metasurface-assisted multimodal quantum imaging.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Entanglement-controlled vectorial meta-holography.Light, science & applications · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yide ZhangCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-9463-3970
Zhe HeCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-8525-3650
Xin TongCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0003-2002-5638
David C GarrettCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-9747-8494
Rui CaoCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0003-4444-7528
Lihong V WangCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0001-9783-4383

Funding

High-speed panoramic 3D photoacoustic computed tomography of the breastR35CA220436 · NCI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI WANG, LIHONG · 2018 to 2024
$6.4M
Label-free intraoperative photoacoustic microscopy for rapid diagnosis of tissue biopsies with specimen integrityR01EB028277 · NIBIB · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI D'APUZZO, MASSIMO, WANG, LIHONG · 2019 to 2022
$2.6M
NCI NIH HHS R35 CA220436NIBIB NIH HHS R01 EB028277
6 · The paper itself

Abstract

Quantum imaging holds potential benefits over classical imaging but has faced challenges such as poor signal-to-noise ratios, low resolvable pixel counts, difficulty in imaging biological organisms, and inability to quantify full birefringence properties. Here, we introduce quantum imaging by coincidence from entanglement (ICE), using spatially and polarization-entangled photon pairs to overcome these challenges. With spatial entanglement, ICE offers higher signal-to-noise ratios, greater resolvable pixel counts, and the ability to image biological organisms. With polarization entanglement, ICE provides quantitative quantum birefringence imaging capability, where both the phase retardation and the principal refractive index axis angle of an object can be remotely and instantly quantified without changing the polarization states of the photons incident on the object. Furthermore, ICE enables 25 times greater suppression of stray light than classical imaging. ICE has the potential to pave the way for quantum imaging in diverse fields, such as life sciences and remote sensing.

Identifiers

PMID38457506
PMCPMC10923495

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.