Evidence map›Paper›PMID 38457439›Full record

ArticleThe journal of physical chemistry. B2024

Molecular Crowding Alters the Interactions of Polymyxin Lipopeptides within the Periplasm of

Iain P S Smith, Conrado Pedebos, Syma Khalid

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physical chemistry. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Surfactin-Induced β-(1,3)-Glucan Exposure inFoods (Basel, Switzerland) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Iain P S SmithSchool of Chemistry, University of Southampton, Southampton SO17 1BJ, U.K.ORCID 0000-0002-1562-3361
Conrado PedebosPrograma de Pós-Graduação em Biociências (PPGBio), Universidade Federal de Ciências da Saúde de Porto Alegre─UFCSPA, Porto Alegre 90050-170, Brazil.
Syma KhalidDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, U.K.ORCID 0000-0002-3694-5044
Universidade Federal de Ciências da Saúde de Porto Alegre · BRUniversity of Oxford · GBUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cell envelope of Gram-negative bacteria is a crowded tripartite architecture that separates the cell interior from the external environment. Two membranes encapsulate the aqueous periplasm, which contains the cell wall. Little is known about the mechanisms via which antimicrobial peptides move through the periplasm from the outer membrane to their site of action, the inner membrane. We utilize all-atom molecular dynamics to study two antimicrobial peptides, polymyxins B1 and E, within models of the

Indexed as

Escherichia coliPeriplasmAnti-Bacterial AgentsLipopeptidesLipoproteinsMolecular Dynamics SimulationPolymyxinsAnti-Bacterial AgentsLipopeptidesLipoproteinsPolymyxins

Identifiers

PMID38457439
PMCPMC10961723
OpenAlexW4392602543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.