Evidence map›Paper›PMID 38457203›Full record

ArticleJMIR research protocols2024

Decreasing Opioid Addiction and Diversion Using Behavioral Economics Applied Through a Digital Engagement Solution: Protocol for a Randomized Controlled Trial.

Rubina Fatima Rizvi, Jamee Ann Schoephoerster, Sagar Satish Desphande, Michael Usher, Andy Elaine Oien, Maya Marie Peters, Matthew Scott Loth, Matthew William Bahr, Steffen Ventz, Joseph Stephen Koopmeiners and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06124079 (The Implementation of a Post-operative Communication App to Improve Pain Control and Opioid Use), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06124079 nacompletednot on this mapstarted 2025, after this paper: background citation

The Implementation of a Post-operative Communication App to Improve Pain Control and Opioid Use

TypeinterventionalSponsorUniversity of MinnesotaRan2025 to 2025Enrolled3,442ConditionsAcute PainArmsOPY interactive messaging service, Standard care
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Health disparities in neurology.Nature reviews. Neurology · 2025
    Review
  2. Leveraging Trauma Informed Care for Digital Health Intervention Development in Opioid Use Disorder.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Rubina Fatima Rizvi *Division of Computational Health Sciences, Department of Surgery, University of Minnesota, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0001-9432-3086
Jamee Ann Schoephoerster *University of Minnesota Medical School, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0002-0037-1480
Sagar Satish DesphandeUniversity of Minnesota Medical School, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0002-6130-613X
Michael UsherUniversity of Minnesota Medical School, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0002-0205-987X
Andy Elaine OienCenter for Learning Health System Sciences, University of Minnesota, Minneapolis, MN, United States.ORCID https://orcid.org/0009-0000-0030-4483
Maya Marie PetersCenter for Learning Health System Sciences, University of Minnesota, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0003-4603-1948
Matthew Scott LothCenter for Learning Health System Sciences, University of Minnesota, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0002-7777-9919
Matthew William BahrM Health Fairview Systems, Minneapolis, MN, United States.ORCID https://orcid.org/0009-0009-2813-7619
Steffen VentzDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0003-2229-9560
Joseph Stephen KoopmeinersCenter for Learning Health System Sciences, University of Minnesota, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0001-6147-3168
Genevieve B MeltonDivision of Computational Health Sciences, Department of Surgery, University of Minnesota, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0001-5193-1663
University of Minnesota · USUniversity of Minnesota System · USFairview Health Services · USUniversity of Minnesota Medical Center · US

Funding

Research Education CoreP30HS029744 · AHRQ · UNIVERSITY OF MINNESOTA · PI MELTON-MEAUX, GENEVIEVE B · 2024 to 2025
$2.0M
AHRQ HHS P30 HS029744
6 · The paper itself

Abstract

backgroundDespite strong and growing interest in ending the ongoing opioid health crisis, there has been limited success in reducing the prevalence of opioid addiction and the number of deaths associated with opioid overdoses. Further, 1 explanation for this is that existing interventions target those who are opiate-dependent but do not prevent opioid-naïve patients from becoming addicted.

objectiveLeveraging behavioral economics at the patient level could help patients successfully use, discontinue, and dispose of their opioid medications in an acute pain setting. The primary goal of this project is to evaluate the effect of the 3 versions of the Opioid Management for You (OPY) tool on measures of opioid use relative to the standard of care by leveraging a pragmatic randomized controlled trial (RCT).

methodsA team of researchers from the Center for Learning Health System Sciences (CLHSS) at the University of Minnesota partnered with M Health Fairview to design, build, and test the 3 versions of the OPY tool: social influence, precommitment, and testimonial version. The tool is being built using the Epic Care Companion (Epic Inc) platform and interacts with the patient through their existing MyChart (Epic Systems Corporation) personal health record account, and Epic patient portal, accessed through a phone app or the MyChart website. We have demonstrated feasibility with pilot data of the social influence version of the OPY app by targeting our pilot to a specific cohort of patients undergoing upper-extremity procedures. This study will use a group sequential RCT design to test the impact of this important health system initiative. Patients who meet OPY inclusion criteria will be stratified into low, intermediate, and high risk of opiate use based on their type of surgery.

resultsThis study is being funded and supported by the CLHSS Rapid Prospective Evaluation and Digital Technology Innovation Programs, and M Health Fairview. Support and coordination provided by CLHSS include the structure of engagement, survey development, data collection, statistical analysis, and dissemination. The project was initially started in August 2022. The pilot was launched in February 2023 and is still running, with the data last counted in August 2023. The actual RCT is planned to start by early 2024.

conclusionsThrough this RCT, we will test our hypothesis that patient opioid use and diverted prescription opioid availability can both be improved by information delivery applied through a behavioral economics lens via sending nudges directly to the opioid users through their personal health record.

trial registrationClinicalTrials.gov NCT06124079; https://clinicaltrials.gov/study/NCT06124079. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/52882.

Indexed as

acute painapplicationbehavioral economicsdigital engagementhealth crisisMyChartnudgesopioidopioid abuseopioid addictionopioid naïve patientsopioid useoverdosepainpersonal health recordphone apppost-operative carerandomized controlled trialRCTtooltoolswebsite

Identifiers

PMID38457203
PMCPMC10960208
OpenAlexW4391182998

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.