Evidence map›Paper›PMID 38456908›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2024

The effect of an endovascular Heaney maneuver to achieve total hepatic isolation on survival, hemodynamic stability, retrohepatic bleeding, and collateral flow in a porcine model.

Maria B Wikström, Anna Stene-Hurtsén, Jens Åström, Tal M Hörer, Kristofer F Nilsson

Abstract read
In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria B WikströmDepartment of Emergency, Arvika Hospital, Region Värmland, Arvika, Sweden. maria.wikstrom@regionvarmland.se.ORCID http://orcid.org/0000-0001-8864-7068
Anna Stene-HurtsénSchool of Medical Sciences, Örebro University, Örebro, Sweden.ORCID http://orcid.org/0000-0003-0646-2508
Jens ÅströmDepartment of Anesthesiology and Intensive Care, Falun Hospital, Falun, Region Dalarna, Sweden.
Tal M HörerDepartment of Cardiothoracic and Vascular Surgery, Department of Surgery, Örebro University Hospital and Faculty of Medicine and Health, Örebro University, Örebro, Region Örebro Län, Sweden.ORCID http://orcid.org/0000-0003-3912-4732
Kristofer F NilssonSchool of Medical Sciences, Örebro University, Örebro, Sweden.ORCID http://orcid.org/0000-0002-8461-5074

Funding

Region Örebro län OLL-843151Region Örebro län OLL-889081Region Örebro län OLL-979942Region Värmland LIV-FOU 967296
6 · The paper itself

Abstract

purposeCombining resuscitative endovascular balloon occlusion of the aorta (REBOA) and the inferior vena cava (REBOVC) with open surgery is a new hybrid approach for treating retrohepatic vena caval injuries. We compared endovascular total hepatic isolation with supraceliac REBOA ± suprahepatic REBOVC and no occlusion in experimental retrohepatic vena cava bleeding regarding survival, bleeding volume, hemodynamic stability, and arterial collateral blood flow.

methodsTwenty-five anesthetized pigs (n = 6-7/group) were randomized to REBOA; REBOA + REBOVC; REBOA + infra and suprahepatic REBOVC + portal vein occlusion (endovascular Heaney maneuver, four-balloon-occlusion, 4BO) or no occlusion. After balloon inflation, free bleeding was initiated from an open sheath in the retrohepatic vena cava. Bleeding volume, right internal thoracic artery (RITA) blood flow, hemodynamics, and arterial blood variables were measured until death or up to 90 min.

resultsThe REBOA group had a longer median survival time (63 min) compared with the 4BO (24 min, P = 0.02) and no occlusion (30 min, P = 0.02) groups, not versus the REBOA + REBOVC group (49 min, P > 0.05). The first 15 min accumulated bleeding was comparable in all groups (P > 0.05); Thereafter, bleeding volume was higher in the REBOA group versus the 4BO group (P < 0.05), not versus the other groups. RITA blood flow and MAP were higher in the REBOA group versus the other groups after 10 min of bleeding (P < 0.05).

conclusionsEndovascular Heaney maneuver was not beneficial for survival or hemodynamic stability in this porcine model, whereas supraceliac REBOA was. Anatomical differences in thoracoabdominal collaterals between pigs and humans must be considered when interpreting these results.

Indexed as

Balloon OcclusionCollateral CirculationEndovascular ProceduresHemodynamicsResuscitationVena Cava, InferiorAnimalsDisease Models, AnimalHemorrhageLiverSwineREBOAREBOVCRetrohepatic inferior vena cavaTrauma

Identifiers

PMID38456908
PMCPMC11458705

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.