ReviewMayo Clinic proceedings2024
Outcomes of Acute Respiratory Failure in Patients With Cancer in the United States.
Review in Mayo Clinic proceedings, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Transesophageal echocardiography and pulmonary artery catheter use and short-term outcomes in patients undergoing coronary artery bypass surgery: A multi-center retrospective study.BMC cardiovascular disorders · 2026Article
- Oncologic and physiologic predictors of mortality after intensive care unit admission in patients with lung cancer.Annals of the American Thoracic Society · 2026Article
- Article
- Construction and validation of a prognostic nomogram for predicting short-term mortality in acute respiratory failure patients: a retrospective cohort study based on the MIMIC-IV database.BMC pulmonary medicine · 2026Article
- Development and external validation of a machine learning model to predict high flow nasal cannula failure.BMJ open respiratory research · 2025Article
- Predicting Outcome and Duration of Mechanical Ventilation in Acute Hypoxemic Respiratory Failure: The PREMIER Study.Journal of clinical medicine · 2025Article
- Clinical risk modeling and epidemiological surveillance of SARI in Cali, Colombia.Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- In-Hospital Mortality and Associated Factors among Colorectal Cancer Patients in Germany.Cancers · 2024Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
Abstract
objectiveTo determine the epidemiological effect-magnitude and outcomes of patients with cancer vs those without cancer who are hospitalized with acute respiratory failure (ARF). PATIENTS AND
methodsWe reviewed hospitalizations within the National Inpatient Sample (NIS) database between January 1, 2016, and December 31, 2018. Patients were classified based on a diagnosis of solid-organ cancer, hematologic cancer, or no cancer. Noninvasive positive pressure ventilation (NIPPV) failure was defined as patients who initially received NIPPV and had progression to invasive mechanical ventilation. Weighted samples were used to derive population estimates.
resultsDuring the study period, there were an estimated 8,837,209 admissions with ARF in the United States, 8.9% (783,625) of which had solid-organ cancer and 2.0% (176,095) had hematologic cancers. Annually, 319,907 patients with cancer are admitted with ARF, with 27.3% (87,302) requiring invasive mechanical ventilation and 10.0% (31,998) requiring NIPPV. In-hospital mortality was higher in patients with cancer vs those without cancer (24.0% [76,813] vs 12.3% [322,465]; P<.001), and this proprotion persisted when stratified by the highest method of oxygen delivery. Patients with cancer had longer hospital length of stay (7.0 days [3.0 to 12.0 days] vs 5.0 days [3.0 to 10.0 days]; P<.001) and were more likely to have NIPPV failure (14.9% [3,992] vs 12.8% [41,875]). Compared with those with solid-organ cancer, patients with hematologic cancers experienced worse outcomes. The association between underlying cancer diagnosis and outcomes remained consistent when adjusted for age, sex, and comorbidities.
conclusionIn the United States, patients with cancer account for over 10% of ARF hospital admissions (959,720 of 8,837,209). They experience an approximately 2-fold higher mortality versus those without cancer. Those with hematologic cancers appear to experience worse outcomes than patients with solid-organ cancers.
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