Evidence map›Paper›PMID 38456679›Full record

ArticlemBio2024

Cryogenic electron tomography reveals novel structures in the apical complex of

Stella Y Sun, Li-Av Segev-Zarko, Grigore D Pintilie, Chi Yong Kim, Sophia R Staggers, Michael F Schmid, Elizabeth S Egan, Wah Chiu, John C Boothroyd

Open access · goldAbstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
11.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. The essential function of the apical polar ring during the blood stage ofbioRxiv : the preprint server for biology · 2026
    Article
  7. Physiology of invasiveFrontiers in cellular and infection microbiology · 2026
    Review
  8. Atomic models of the Toxoplasma cell invasion machinery.Nature structural & molecular biology · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Cryo-ET reveals the in situ architecture of the polar tube invasion apparatus from microsporidian parasites.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Architecture of theProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Missing Wedge Completion via Unsupervised Learning with Coordinate Networks.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Stella Y Sun *Department of Structural Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-9004-8494
Li-Av Segev-Zarko *Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0003-4151-5513
Grigore D PintilieDepartment of Bioengineering, James H. Clark Center, Stanford University, Stanford, California, USA.
Chi Yong KimDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
Sophia R StaggersDepartment of Structural Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-8157-6372
Michael F SchmidDivision of Cryo-EM and Bioimaging, SSRL, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, California, USA.
Elizabeth S EganDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
Wah ChiuDepartment of Bioengineering, James H. Clark Center, Stanford University, Stanford, California, USA.
John C BoothroydDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
Stanford University · USClark University · USSLAC National Accelerator Laboratory · USUniversity of Pittsburgh · US

Funding

Unified Data Resource for Large Complexes Determined by Cryo-Electron MicroscopyR01GM079429 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH · 2007 to 2021
$11.6M
Identifying critical erythrocyte host factors for Plasmodium falciparum malariaDP2HL137186 · NHLBI · STANFORD UNIVERSITY · PI EGAN, ELIZABETH S. · 2016 to 2016
$2.4M
NHLBI NIH HHS DP2 HL137186NIGMS NIH HHS R01 GM079429
6 · The paper itself

Abstract

Intracellular infectious agents, like the malaria parasite, IMPORTANCE: Malaria is an infectious disease caused by parasites of the genus

Indexed as

MalariaParasitesPlasmodiumToxoplasmaAnimalsElectron Microscope TomographyHost-Parasite InteractionsPlasmodium falciparumProtozoan ProteinsProtozoan Proteinsapical ringcryo-electron tomographyPlasmodium falciparumrhoptrysubtomogram averagingToxoplasma gondii

Identifiers

PMID38456679
PMCPMC11005440
OpenAlexW4392585893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.