Evidence map›Paper›PMID 38456193›Full record

ArticleOpen forum infectious diseases2024

Sex and HIV Differences in Preserved Ratio Impaired Spirometry (PRISm) Among Ugandans Postpneumonia.

Rebecca A Abelman, Jessica Fitzpatrick, Katerina L Byanova, Josephine Zawedde, Ingvar Sanyu, Patrick Byanyima, Emmanuel Musisi, Jenny Hsieh, Michelle Zhang, Jake Branchini and 7 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Rebecca A AbelmanDivision of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0003-3040-1879
Jessica FitzpatrickDivision of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Katerina L ByanovaDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Josephine ZaweddeInfectious Diseases Research Collaboration, Kampala, Uganda.
Ingvar SanyuInfectious Diseases Research Collaboration, Kampala, Uganda.
Patrick ByanyimaInfectious Diseases Research Collaboration, Kampala, Uganda.
Emmanuel MusisiDivision of Infection and Global Health, School of Medicine, University of St. Andrews, St. Andrews, UK.
Jenny HsiehDepartment of Anesthesia and Critical Care, University of California San Francisco, San Francisco, California, USA.
Michelle ZhangDivision of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Jake BranchiniDivision of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Abdul SessoloInfectious Diseases Research Collaboration, Kampala, Uganda.
Peter W HuntDivision of Experimental Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0002-4571-4870
Rejani LalithaDivision of Pulmonary Medicine, Department of Medicine, Makerere College of Health Sciences, Kampala, Uganda.
J Lucian DavisDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, USA.
Kristina CrothersDivision of Pulmonary, Critical Care and Sleep, Department of Medicine, Veterans Affairs (VA) Puget Sound Health Care System and University of Washington, Seattle, Washington, USA.
William WorodriaDivision of Pulmonary Medicine, Department of Medicine, Makerere College of Health Sciences, Kampala, Uganda.
Laurence HuangDivision of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
University of California, San Francisco · USInfectious Diseases Research Collaboration · UGMakerere University · UGMulago Hospital · UGUniversity of St Andrews · GBUniversity of Washington · USYale University · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Inflammation, Aging, Microbes, Obstructive Lung Disease and Diffusion Abnormalities (I AM OLD-DA) Study - Diversity SupplementR01HL128156 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, LAURENCE, HUNT, PETER W · 2015 to 2024
$7.1M
Training in HIV Translational ResearchT32AI060530 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Diane V Havlir · 2005 to 2026
$6.4M
Integrated Analysis of Microbial and Genomic data in Obstructive Lung Disease (I AM GOLD) StudyR01HL143998 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTENSON, STEPHANIE A, HUANG, LAURENCE · 2019 to 2022
$3.2M
UCSF Career Development Program in Cardiopulmonary, Hematologic, and Immunologic Comorbidities of HIV (CHIC)K12HL143961 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HSUE, PRISCILLA Y., HUANG, LAURENCE · 2018 to 2022
$1.8M
Persistent Functional Immune Defects in Treated HIV InfectionK24AI145806 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUNT, PETER W · 2020 to 2024
$921k
NHLBI NIH HHS K12 HL143961NHLBI NIH HHS R01 HL128156NHLBI NIH HHS R01 HL143998NIAID NIH HHS K24 AI145806NIAID NIH HHS P30 AI027763NIAID NIH HHS T32 AI060530
6 · The paper itself

Abstract

Background: Preserved ratio impaired spirometry (PRISm), defined as a normal ratio of forced expiratory volume in 1 second (FEV Methods: Adults with and without HIV underwent baseline followed by serial spirometry after completing therapy for pneumonia, predominantly tuberculosis (TB), in Kampala, Uganda. Using generalized estimating equations adjusted for age, body mass index, smoking, biomass fuel exposure, HIV, and TB status, we compared individuals with PRISm with those with normal spirometry. These models were stratified by HIV status. Results: Of 339 baseline participants, 153 (45%) were women; 129 (38%) had HIV, of whom 53% were women. Overall, 105/339 participants (31%) had PRISm at baseline. HIV was associated with lower odds of PRISm (adjusted odds ratio [aOR], 0.38; 95% CI, 0.21-0.68; Conclusions: Among Ugandan adults who recovered from pneumonia, female sex was associated with increased odds and HIV with decreased odds of PRISm, suggesting independent sex and HIV effects on PRISm pathogenesis.

Indexed as

HIVpreserved ratio impaired spirometrysex differencestuberculosis

Identifiers

PMID38456193
PMCPMC10919919
OpenAlexW4391091638

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.