Evidence map›Paper›PMID 38456074›Full record

ArticleFrontiers in epidemiology2024

Transporting results in an observational epidemiology setting: purposes, methods, and applied example.

Ghislaine Scelo, Daniela Zugna, Maja Popovic, Katrine Strandberg-Larsen, Lorenzo Richiardi

Abstract read
In one paragraph

Article in Frontiers in epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ghislaine SceloDepartment of Medical Sciences, University of Turin, CPO-Piemonte, Turin, Italy.
Daniela ZugnaDepartment of Medical Sciences, University of Turin, CPO-Piemonte, Turin, Italy.
Maja PopovicDepartment of Medical Sciences, University of Turin, CPO-Piemonte, Turin, Italy.
Katrine Strandberg-LarsenSection of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Lorenzo RichiardiDepartment of Medical Sciences, University of Turin, CPO-Piemonte, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the medical domain, substantial effort has been invested in generating internally valid estimates in experimental as well as observational studies, but limited effort has been made in testing generalizability, or external validity. Testing the external validity of scientific findings is nevertheless crucial for the application of knowledge across populations. In particular, transporting estimates obtained from observational studies requires the combination of methods for causal inference and methods to transport the effect estimates in order to minimize biases inherent to observational studies and to account for differences between the study and target populations. In this paper, the conceptual framework and assumptions behind transporting results from a population-based study population to a target population is described in an observational setting. An applied example to life-course epidemiology, where internal validity was constructed for illustrative purposes, is shown by using the targeted maximum likelihood estimator.

Indexed as

birth cohortsexternal validityobservational researchTMLEtransportability

Identifiers

PMID38456074
PMCPMC10910888

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.