Evidence map›Paper›PMID 38456040›Full record

ArticleRSC chemical biology2024

Cationic dextrin nanoparticles for effective intracellular delivery of cytochrome

Ankita Sarkar, Sanchita Sarkhel, Deepali Bisht, Amit Jaiswal

Abstract read
In one paragraph

Article in RSC chemical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ankita SarkarSchool of Biosciences and Bioengineering, Indian Institute of Technology Mandi Kamand Mandi 175075 Himachal Pradesh India j.amit@iitmandi.ac.in.
Sanchita SarkhelSchool of Biosciences and Bioengineering, Indian Institute of Technology Mandi Kamand Mandi 175075 Himachal Pradesh India j.amit@iitmandi.ac.in.
Deepali BishtSchool of Biosciences and Bioengineering, Indian Institute of Technology Mandi Kamand Mandi 175075 Himachal Pradesh India j.amit@iitmandi.ac.in.
Amit JaiswalSchool of Biosciences and Bioengineering, Indian Institute of Technology Mandi Kamand Mandi 175075 Himachal Pradesh India j.amit@iitmandi.ac.in.ORCID https://orcid.org/0000-0002-9748-0404

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular protein delivery shows promise as a selective and specific approach to cancer therapy. However, a major challenge is posed by delivering proteins into the target cells. Despite the development of nanoparticle (NP)-based approaches, a versatile and biocompatible delivery system that can deliver active therapeutic cargo into the cytosol while escaping endosome degradation remains elusive. In order to overcome these challenges, a polymeric nanocarrier was prepared using cationic dextrin (CD), a biocompatible and biodegradable polymer, to encapsulate and deliver cytochrome

Identifiers

PMID38456040
PMCPMC10915965

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.