Evidence map›Paper›PMID 38456038›Full record

ReviewRSC chemical biology2024

Sialic acids in infection and their potential use in detection and protection against pathogens.

Simone Dedola, Sanaz Ahmadipour, Peterson de Andrade, Alexander N Baker, Andrew N Boshra, Simona Chessa, Matthew I Gibson, Pedro J Hernando, Irina M Ivanova, Jessica E Lloyd and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in RSC chemical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Simone DedolaDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.ORCID https://orcid.org/0009-0003-5346-508X
Sanaz AhmadipourDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.
Peterson de AndradeDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.
Alexander N BakerDepartment of Chemistry, University of Warwick Gibbet Hill Road Coventry CV4 7AL UK.ORCID https://orcid.org/0000-0001-6019-3412
Andrew N BoshraDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.
Simona ChessaIceni Glycoscience Ltd, Norwich Research Park Norwich NR4 7TJ UK simone.dedola@iceniglycoscience.com.
Matthew I GibsonDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.ORCID https://orcid.org/0000-0002-8297-1278
Pedro J HernandoIceni Glycoscience Ltd, Norwich Research Park Norwich NR4 7TJ UK simone.dedola@iceniglycoscience.com.ORCID https://orcid.org/0009-0003-8173-4048
Irina M IvanovaIceni Glycoscience Ltd, Norwich Research Park Norwich NR4 7TJ UK simone.dedola@iceniglycoscience.com.
Jessica E LloydDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.ORCID https://orcid.org/0000-0002-6346-6321
María J MarínSchool of Chemistry, University of East Anglia, Norwich Research Park Norwich NR4 7TJ UK.ORCID https://orcid.org/0000-0001-8021-5498
Alexandra J Munro-ClarkDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.
Giulia PergolizziIceni Glycoscience Ltd, Norwich Research Park Norwich NR4 7TJ UK simone.dedola@iceniglycoscience.com.
Sarah-Jane RichardsDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.
Iakovia TtofiDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.ORCID https://orcid.org/0000-0002-3728-3628
Ben A WagstaffDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.
Robert A FieldDepartment of Chemistry and Manchester Institute of Biotechnology, University of Manchester 131 Princess Street Manchester M1 7DN UK robert.field@manchester.ac.uk.ORCID https://orcid.org/0000-0001-8574-0275
University of Manchester · GBNorwich Research Park · GBUniversity of East Anglia · GBUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In structural terms, the sialic acids are a large family of nine carbon sugars based around an alpha-keto acid core. They are widely spread in nature, where they are often found to be involved in molecular recognition processes, including in development, immunology, health and disease. The prominence of sialic acids in infection is a result of their exposure at the non-reducing terminus of glycans in diverse glycolipids and glycoproteins. Herein, we survey representative aspects of sialic acid structure, recognition and exploitation in relation to infectious diseases, their diagnosis and prevention or treatment. Examples covered span influenza virus and Covid-19,

Identifiers

PMID38456038
PMCPMC10915975
OpenAlexW4389937611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.