ReviewFrontiers in epidemiology2023
Mortality, and life expectancy in Epilepsy and Status epilepticus-current trends and future aspects.
Review in Frontiers in epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05934903 (Feasibility Study), which is not on this map. Cited by 65 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility Study: tDCS for Treatment of Refractory Status Epilepticus
Who cites it
65 citing papers in PubMed, 6 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Associations between duration of status epilepticus and clinical outcomes in adults: a systematic review.Journal of neurology · 2026Pooled it
- Prevalence and associated factors of depression among adult patients with epilepsy in Ethiopia: a systematic review and meta-analysis, 2025.BMC psychiatry · 2025Pooled it
- Mortality in patients with epilepsy: a systematic review.Journal of neurology · 2025Pooled it
- Efficacy and safety of stiripentol in the prevention and cessation of status epilepticus: A systematic review.Epilepsia open · 2024Pooled it
- Immunomodulatory interventions for focal epilepsy.The Cochrane database of systematic reviews · 2023Pooled it
- A systematic review of non-invasive biomarkers for seizure forecasting in pediatric epilepsy patients.Frontiers in neurologyPooled it
- Benzodiazepines in Epilepsy: A US Perspective on Clinical Use, Pharmacology, Abuse Methods, and Public Health Considerations.Neurology and therapy · 2026Review
- Evaluation of current practices and communication surrounding sudden unexpected death in epilepsy (SUDEP): A survey analysis of healthcare practitioners.Epilepsia open · 2026Article
- Distinct clinical clusters of paediatric patients with status epilepticus: Retrospective cohort study.Developmental medicine and child neurology · 2026Article
- A Predictive Model for Short-Term Mortality After Status Epilepticus: The ACARD Score.Neurology · 2026Article
- The prevalence and determinants of epilepsy in Ghana: A population-based study in two districts using a three-stage approach.Epilepsia · 2026Article
- A multi-target approach using Moringa oleifera leaf extract in ameliorating PTZ-induced epilepsy-like neurobehavior in male rats: in vivo and in silico study.Metabolic brain disease · 2026Article
- Community perspectives and recommendations to reduce epilepsy stigma and enhance effective management of epilepsy in Uganda: A qualitative study.Epilepsy & behavior : E&B · 2026Article
- Review
- GABACellular and molecular neurobiology · 2026Review
- Immunomodulatory Effects of Anti-Epileptic Drug Lacosamide on Mammalian Macrophages.Cell biochemistry and biophysics · 2026Article
- Defining the end point of status epilepticus: A scoping review and framework for standardization.Epilepsia · 2026Article
- Cyclic Recurrence of Seizures as a Marker for Super-Refractory Status Epilepticus.Brain and behavior · 2026Article
- Evaluating Treatment Dynamics in Refractory Status Epilepticus: A Retrospective Observational Cohort Study.The Neurohospitalist · 2026Article
- Health Challenges in Vulnerable Populations: Neurological and Vascular Diseases Among People Experiencing Homelessness in Gdańsk, Poland: An Observational Study.Journal of clinical medicine · 2026Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with epilepsy carry a risk of premature death which is on average two to three times higher than in the general population. The risk of death is not homogenously distributed over all ages, etiologies, and epilepsy syndromes. People with drug resistant seizures carry the highest risk of death compared to those who are seizure free, whose risk is similar as in the general population. Most of the increased risk is directly related to the cause of epilepsy itself. Sudden unexplained death in epilepsy patients (SUDEP) is the most important cause of epilepsy-related deaths especially in the young and middle-aged groups. Population based studies with long-term follow up demonstrated that the first years after diagnosis carry the highest risk of death, while in the later years the mortality decreases. Improved seizure control and being exposed to a specialized comprehensive care centre may help to reduce the risk of death in patients with epilepsy. The mortality of status epilepticus is substantially increased with case fatality rates between 4.6% and 39%, depending on its cause and duration, and the age of the population studied. The epidemiological data on overall and cause specific mortality as well as their determinants and risk factors are critically reviewed and methodological issues pertinent to the studies on mortality of epilepsy and Status epilepticus are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.