Evidence map›Paper›PMID 38455846›Full record

ArticleFrontiers in physiology2024

β3-Adrenoceptor as a new player in the sympathetic regulation of the renal acid-base homeostasis.

Serena Milano, Ilenia Saponara, Andrea Gerbino, Dominga Lapi, Ludovica Lela, Monica Carmosino, Massimo Dal Monte, Paola Bagnoli, Maria Svelto, Giuseppe Procino

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Serena MilanoDepartment of Biosciences, Biotechnologies and Environment, University of Bari, Bari, Italy.
Ilenia SaponaraDepartment of Biosciences, Biotechnologies and Environment, University of Bari, Bari, Italy.
Andrea GerbinoDepartment of Biosciences, Biotechnologies and Environment, University of Bari, Bari, Italy.
Dominga LapiDepartment of Biology, University of Pisa, Pisa, Italy.
Ludovica LelaDepartment of Sciences, University of Basilicata, Potenza, Italy.
Monica CarmosinoDepartment of Sciences, University of Basilicata, Potenza, Italy.
Massimo Dal MonteDepartment of Biology, University of Pisa, Pisa, Italy.
Paola BagnoliDepartment of Biology, University of Pisa, Pisa, Italy.
Maria SveltoDepartment of Biosciences, Biotechnologies and Environment, University of Bari, Bari, Italy.
Giuseppe ProcinoDepartment of Biosciences, Biotechnologies and Environment, University of Bari, Bari, Italy.
University of Bari Aldo Moro · ITUniversity of Pisa · ITUniversity of Basilicata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efferent sympathetic nerve fibers regulate several renal functions activating norepinephrine receptors on tubular epithelial cells. Of the beta-adrenoceptors (β-ARs), we previously demonstrated the renal expression of β3-AR in the thick ascending limb (TAL), the distal convoluted tubule (DCT), and the collecting duct (CD), where it participates in salt and water reabsorption. Here, for the first time, we reported β3-AR expression in the CD intercalated cells (ICCs), where it regulates acid-base homeostasis. Co-localization of β3-AR with either proton pump H

Indexed as

acid–base balanceacid loadingH+-ATPasePKAβ3-adrenoceptor

Identifiers

PMID38455846
PMCPMC10917900
OpenAlexW4392057369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.