ArticleFrontiers in cardiovascular medicine2024
Virtual calcium removal in calcified coronary arteries with photon-counting detector CT-first
Article in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- Improvements in the Diagnostic Performance of Coronary Computed Tomography Angiography in the Assessment of Heavily Calcified Plaques Using a Novel Deep Learning Model.Reviews in cardiovascular medicine · 2026Article
- A personalized iodine delivery rate-based injection protocol in coronary angiography on photon-counting CT.European radiology · 2026Article
- Response to "Photon-Counting CT in Cardiovascular Imaging: From Technical Promise to Clinical Translation".Korean journal of radiology · 2026Article
- Clinical benefits and current challenges of photon-counting detector CT in vascular imaging.Radiology advances · 2026Review
- Diagnostic Performance of Photon-Counting CT Angiography in Vascular Stenosis Assessment: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2026Review
- Photon-Counting CT in Cardiovascular Imaging: Clinical Applications.Korean journal of radiology · 2026Review
- Cardiac imaging using photon counting CT - benefits, challenges and prospects.The international journal of cardiovascular imaging · 2026Review
- Ultra-high spatial resolution at photon-counting computed tomography: technical insights and sustainable applications in cardiothoracic imaging.European radiology experimental · 2026Review
- Spectral ultrahigh-resolution photon-counting CT for coronary stent imaging: evaluation in a dynamic phantom.European radiology experimental · 2025Article
- Coronary angiography with photon-counting detector CT-new options and some critical decisions.The British journal of radiology · 2025Review
- Spectral Imaging Techniques in Heart Disease Assessment Using Photon-Counting Detector Computed Tomography.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Accuracy and consistency of subtraction dual-layer spectral computed tomography in diagnosing coronary stenosis: invasive coronary angiography validation study.Quantitative imaging in medicine and surgery · 2025Article
- Quantification of abdominal aortic calcification using photon-counting CT angiography: an imaging biomarker for high-risk cardiovascular patients.La Radiologia medica · 2025Article
- The pericoronary adipose tissue attenuation in CT strongly depends on kernels and iterative reconstructions.European radiology · 2025Article
- Multienergy cardiovascular CT imaging: current state and future.The British journal of radiology · 2025Review
- The Role of Advanced Cardiac Imaging in Monitoring Cardiovascular Complications in Patients with Extracardiac Tumors: A Descriptive Review.Journal of cardiovascular development and disease · 2024Review
- Technical principles, benefits, challenges, and applications of photon counting computed tomography in coronary imaging: a narrative review.Cardiovascular diagnosis and therapy · 2024Review
- Review: The Role of Dual-Energy Computed Tomography in Detecting Monosodium Urate Deposits in Vascular Tissues.Current rheumatology reports · 2024Review
- Dual-Energy and Photon-Counting Computed Tomography in Vascular Applications-Technical Background and Post-Processing Techniques.Diagnostics (Basel, Switzerland) · 2024Review
- Photon-Counting Detector Computed Tomography (PCD-CT): A New Era for Cardiovascular Imaging? Current Status and Future Outlooks.Journal of cardiovascular development and disease · 2024Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To evaluate the feasibility and accuracy of quantification of calcified coronary stenoses using virtual non-calcium (VNCa) images in coronary CT angiography (CCTA) with photon-counting detector (PCD) CT compared with quantitative coronary angiography (QCA). Materials and methods: This retrospective, institutional-review board approved study included consecutive patients with calcified coronary artery plaques undergoing CCTA with PCD-CT and invasive coronary angiography between July and December 2022. Virtual monoenergetic images (VMI) and VNCa images were reconstructed. Diameter stenoses were quantified on VMI and VNCa images by two readers. 3D-QCA served as the standard of reference. Measurements were compared using Bland-Altman analyses, Wilcoxon tests, and intraclass correlation coefficients (ICC). Results: Thirty patients [mean age, 64 years ± 8 (standard deviation); 26 men] with 81 coronary stenoses from calcified plaques were included. Ten of the 81 stenoses (12%) had to be excluded because of erroneous plaque subtraction on VNCa images. Median diameter stenosis determined on 3D-QCA was 22% (interquartile range, 11%-35%; total range, 4%-88%). As compared with 3D-QCA, VMI overestimated diameter stenoses (mean differences -10%, Conclusion: First experience in mainly minimal to moderate stenoses suggests that virtual calcium removal in CCTA with PCD-CT, when feasible, has the potential to improve the quantification of calcified stenoses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.