Evidence map›Paper›PMID 38455708›Full record

ReviewTherapeutic advances in medical oncology2024

Geographic differences in lung cancer: focus on carcinogens, genetic predisposition, and molecular epidemiology.

Juan Carlos Laguna, Miguel García-Pardo, Joao Alessi, Carlos Barrios, Navneet Singh, Humaid O Al-Shamsi, Herbert Loong, Miquel Ferriol, Gonzalo Recondo, Laura Mezquita

Registry-linked trialAbstract readReview
In one paragraph

Review in Therapeutic advances in medical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06494800 (Added Value of 18F-FDG PET/CT in Lung Cancer), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06494800 unknown statusnot on this map

Added Value of 18F-FDG PET/CT in Lung Cancer

TypeobservationalSponsorSohag UniversityRan2024 to 2025Enrolled30ConditionsLung CancerArmsTrue cut needle biobsy
3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Juan Carlos LagunaMedical Oncology Department, Hospital Clinic of Barcelona, Barcelona, Spain.
Miguel García-PardoDepartment of Medical Oncology, Hospital Universitario Ramón y Cajal, Madrid, Spain.ORCID https://orcid.org/0000-0001-6339-8501
Joao AlessiLowe Center for Thoracic Oncology, Dana-Farber Cancer Institute.
Carlos BarriosSchool of Medicine, Porto Alegre, Rio Grande do Sul, Brazil.
Navneet SinghPostgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Humaid O Al-ShamsiBurjeel Medical City, Abu Dhabi, United Arab Emirates.
Herbert LoongDepartment of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Miquel FerriolLaboratory of Translational Genomics and Targeted Therapies in Solid Tumors, IDIBAPS, Barcelona, Spain.
Gonzalo RecondoMedical Oncology Department, CEMIC, Buenos Aires, Argentina.
Laura MezquitaMedical Oncology Department, Hospital Clinic of Barcelona, Calle Villarroel 170, Barcelona 08036, Spain.ORCID https://orcid.org/0000-0003-0936-7338

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer poses a global health challenge and stands as the leading cause of cancer-related deaths worldwide. However, its incidence, mortality, and characteristics are not uniform across all regions worldwide. Understanding the factors contributing to this diversity is crucial in a prevalent disease where most cases are diagnosed in advanced stages. Hence, prevention and early diagnosis emerge as the most efficient strategies to enhance outcomes. In Western societies, tobacco consumption constitutes the primary risk factor for lung cancer, accounting for up to 90% of cases. In other geographic locations, different significant factors play a fundamental role in disease development, such as individual genetic predisposition, or exposure to other carcinogens such as radon gas, environmental pollution, occupational exposures, or specific infectious diseases. Comprehensive clinical and molecular characterization of lung cancer in recent decades has enabled us to distinguish different subtypes of lung cancer with distinct phenotypes, genotypes, immunogenicity, treatment responses, and survival rates. The ultimate goal is to prevent and individualize lung cancer management in each community and improve patient outcomes.

Indexed as

geographic differencesmolecular diagnosismolecular epidemiologyNSCLC

Identifiers

PMID38455708
PMCPMC10919138

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.