Evidence map›Paper›PMID 38455688›Full record

ArticleEuropean journal of case reports in internal medicine2024

A Case of Amyloid Goitre in Heavy Chain Amyloidosis: Diagnostic Challenges and Clinical Implications.

Francisco Laranjeira, Bernardo Neves, Paulo Bernardo, Francisco do Rosário, Otília Fernandes, Evelina Mendonça, Ana Catarino

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of case reports in internal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Francisco LaranjeiraDepartment of Internal Medicine, Hospital da Luz, Lisbon, Portugal.
Bernardo NevesDepartment of Internal Medicine, Hospital da Luz, Lisbon, Portugal.
Paulo BernardoDepartment of Hematology, Hospital da Luz, Lisbon, Portugal.
Francisco do RosárioDepartment of Endocrinology, Hospital da Luz, Lisbon, Portugal.
Otília FernandesDepartment of Radiology, Hospital da Luz, Lisbon, Portugal.
Evelina MendonçaDepartment of Clinical Pathology, Hospital da Luz, Lisbon, Portugal.
Ana CatarinoDepartment of Clinical Pathology, Hospital da Luz, Lisbon, Portugal.
Hospital da Luz · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin heavy chain amyloidosis (AH amyloidosis) is an extremely rare subtype of immunoglobulin-derived amyloidosis and there is limited literature on how to diagnose and manage this disorder. We describe a rare case of AH amyloidosis with amyloid goitre and the importance of mass spectrometry in the identification of the different types of amyloids. While additional studies are needed, several observations suggest important practical implications, including differences in clinical picture, prognosis, and pathologic diagnosis. LEARNING POINTS: Immunoglobulin heavy chain amyloidosis is an extremely rare subtype of immunoglobulin-derived amyloidosis and amyloid goitre is even rarer.There is limited literature on how to diagnose and manage this disorder.This case portrays one of these cases - one of the few existing in the literature - and reinforces the diagnostic complexity of this entity.

Indexed as

amyloid goitreHeavy chain amyloidosismass spectrometryTru-Cut biopsy

Identifiers

PMID38455688
PMCPMC10917402
OpenAlexW4391448439

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.