Evidence map›Paper›PMID 38455625›Full record

ArticleNarra J2023

Vitamin D3 induces stem cell activation via Lgr5-Bmi1 expression and improving mouse colitis histology index.

Satrio Wibowo, Almira Pramadhani, Krisni Subandiyah, Sri Poeranto, Kusworini Handono

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Narra J, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Satrio WibowoDepartment of Pediatrics, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Almira PramadhaniFaculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Krisni SubandiyahDepartment of Pediatrics, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Sri PoerantoDepartment of Parasitology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Kusworini HandonoDepartment of Clinical Pathology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
University of Brawijaya · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional therapy for inflammatory bowel disease using long-term anti-inflammatory drugs does not seem to provide optimal results. Adjuvant therapy using vitamin D3 is believed to have an essential role in repairing the colonic mucosa through the activation of colonic stem cells. The aim of this study was to demonstrate the effect of vitamin D3 in mucosal repair through stem cell activation, marked by leucin-rich repeat-containing G protein-coupled receptor 5 (Lgr5) and B lymphoma Mo-MLV insertion region 1 (Bmi1) expression and decrease the mouse colitis histology index (MCHI) score. In this study, 50

Indexed as

Colitishistologymucosastem cellvitamin D3

Identifiers

PMID38455625
PMCPMC10919439
OpenAlexW4388745760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.