ReviewNarra J2023
Etiopathogenesis of adolescent idiopathic scoliosis (AIS): Role of genetic and environmental factors.
Review in Narra J, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Global prevalence and associated risk factors of scoliosis in children and adolescents: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Clinical Features in Children with Persistent Toe Walking Who Carry Heterozygous PYGM Variants: A Cross-Sectional Study.Journal of musculoskeletal & neuronal interactions · 2026Article
- Epidemiological investigation of adolescent idiopathic scoliosis and evaluation of the therapeutic effect of an integrated sports and medicine rehabilitation strategy for scoliosis treatment.Frontiers in public health · 2026Article
- The preventive effect of emergency psychological intervention on post-traumatic stress disorder (PTSD) in patients with acute spinal cord injury: a retrospective cohort study.BMC emergency medicine · 2025Article
- Examination of the coexistence of scoliosis and hallux valgus in females.Acta orthopaedica et traumatologica turcica · 2025Article
- Assessment and Management of Adolescent Idiopathic Scoliosis: From the Perspective of a Physiatrist.Annals of rehabilitation medicine · 2025Article
- Adolescent scoliosis in autism spectrum disorder: is it idiopathic or syndromic??Journal of orthopaedic surgery and research · 2025Article
- Association between bone mineral density and scoliosis: a two-sample mendelian randomization study in european populations.Hereditas · 2024Article
- Genetics and pathogenesis of scoliosis.North American Spine Society journal · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adolescent idiopathic scoliosis (AIS) has been known to be related closely to genetic factors. Higher prevalence of AIS among individuals with family history of scoliosis suggesting critical roles of genetic in the pathogenesis of AIS. However, evidence also suggested that environmental factors such as latitude and sun exposure also play a critical role in the pathogenesis of the disease. While genetic factors played an important role in the occurrence of AIS, environmental factors are more likely to affect the progression of the disease. Although the pathogenesis of AIS remains elusive, current knowledge suggests that genetic factors and its interaction with environmental factors are crucial in the development of the disease, explaining differences in clinical characteristics of AIS across the globe. The aim of this review is to summarize the current knowledge of genetic and environmental factors contributing to AIS and their interactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.