Evidence map›Paper›PMID 38455479›Full record

ArticleAnnals of gastroenterological surgery2024

Albumin-indocyanine green evaluation of future liver remnant predicts liver failure after anatomical hepatectomy for hepatocellular carcinoma: A dual-center retrospective study.

Tomoyuki Nagaoka, Kohei Ogawa, Katsunori Sakamoto, Taro Nakamura, Yoshinori Imai, Yusuke Nishi, Masahiko Honjo, Kei Tamura, Naotake Funamizu, Yasutsugu Takada

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Liver Resection for Hepatocellular Carcinoma: Recent Advances.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tomoyuki NagaokaDepartment of Hepato-Biliary-Pancreatic and Breast Surgery Ehime University Graduate School of Medicine Toon Japan.ORCID https://orcid.org/0000-0002-7635-9955
Kohei OgawaDepartment of Hepato-Biliary-Pancreatic and Breast Surgery Ehime University Graduate School of Medicine Toon Japan.
Katsunori SakamotoDepartment of Hepato-Biliary-Pancreatic and Breast Surgery Ehime University Graduate School of Medicine Toon Japan.ORCID https://orcid.org/0000-0002-6431-0011
Taro NakamuraDepartment of Hepato-Biliary-Pancreatic Surgery Uwajima City Hospital Uwajima Japan.
Yoshinori ImaiDepartment of General Surgery Uwajima City Hospital Uwajima Japan.
Yusuke NishiDepartment of Hepato-Biliary-Pancreatic and Breast Surgery Ehime University Graduate School of Medicine Toon Japan.
Masahiko HonjoDepartment of Hepato-Biliary-Pancreatic and Breast Surgery Ehime University Graduate School of Medicine Toon Japan.ORCID https://orcid.org/0000-0001-9642-4155
Kei TamuraDepartment of Hepato-Biliary-Pancreatic and Breast Surgery Ehime University Graduate School of Medicine Toon Japan.
Naotake FunamizuDepartment of Hepato-Biliary-Pancreatic and Breast Surgery Ehime University Graduate School of Medicine Toon Japan.
Yasutsugu TakadaDepartment of Hepato-Biliary-Pancreatic and Breast Surgery Ehime University Graduate School of Medicine Toon Japan.ORCID https://orcid.org/0000-0001-9743-1840

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The albumin-indocyanine green evaluation (ALICE) score is a useful predictor of post-hepatectomy liver failure (PHLF); however, its usefulness in combination with future liver remnant (FLR), measured by 3-D volumetry, has not been investigated. This study aimed to investigate the relationship between the ALICE of the FLR (ALICE-FLR) score and severe PHLF. Methods: The clinical data of 215 patients who underwent anatomical hepatectomy for hepatocellular carcinoma without portal vein embolization at two institutes between January 2010 and December 2021 were analyzed retrospectively. PHLF occurrence and severity were determined according to the International Study Group of Liver Surgery's definition. Grades B and C PHLF were defined as severe PHLF. The ALICE-FLR, ALICE scores, and indocyanine green clearance of FLR (ICGK-FLR) were evaluated for severe PHLF prediction. Results: Severe PHLF was observed in 40 patients (18.6%). The areas under the curve (AUCs) for the ALICE-FLR, ALICE scores, ICGK-FLR, and FLR were 0.76, 0.64, 0.73, and 0.69, respectively. The AUC of the ALICE-FLR score was significantly higher than that of the ALICE score. The ALICE-FLR score was identified as an independent predictor of severe PHLF (the odds ratio for every 0.01 increment in the ALICE-FLR score was 1.24; 95% confidence interval, 1.070-1.453; Conclusion: The combination of liver function models, including indocyanine green, albumin, and FLR is considered compatible for predicting severe PHLF.

Indexed as

albuminhepatectomyhepatocellular carcinomaindocyanine greenliver failure

Identifiers

PMID38455479
PMCPMC10914702

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.