Evidence map›Paper›PMID 38455426›Full record

ArticleAmerican journal of cancer research2024

Neuron-derived neurotensin promotes pancreatic cancer invasiveness and gemcitabine resistance via the NTSR1/Akt pathway.

Yu-Hsuan Hung, Hui-Ching Wang, Shih-Han Hsu, Li-Yun Wang, Ya-Li Tsai, Yung-Yeh Su, Wen-Chun Hung, Li-Tzong Chen

Open access · bronzeAbstract read
In one paragraph

Article in American journal of cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. First-in-human evaluation of [Annals of medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yu-Hsuan HungDepartment of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung 807, Taiwan.
Hui-Ching WangDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung 807, Taiwan.
Shih-Han HsuNational Institute of Cancer Research, National Health Research Institutes Tainan 704, Taiwan.
Li-Yun WangResearch Center for Animal Biologics, National Pingtung University of Science and Technology Pingtung 912, Taiwan.
Ya-Li TsaiNational Institute of Cancer Research, National Health Research Institutes Tainan 704, Taiwan.
Yung-Yeh SuNational Institute of Cancer Research, National Health Research Institutes Tainan 704, Taiwan.
Wen-Chun HungNational Institute of Cancer Research, National Health Research Institutes Tainan 704, Taiwan.
Li-Tzong ChenNational Institute of Cancer Research, National Health Research Institutes Tainan 704, Taiwan.
Kaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perineural invasion and neurogenesis are frequently observed in pancreatic ductal adenocarcinoma (PDAC) and link to poor outcome. However, how neural factors affect PDAC prognosis and the underlying mechanism as well as counteracting therapeutic are still unclear.

Indexed as

AktNeuronneurotensinneurotensin receptor 1pancreatic ductal adenocarcinoma

Identifiers

PMID38455426
PMCPMC10915311
OpenAlexW4394766719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.