Evidence map›Paper›PMID 38455287›Full record

ArticleFrontiers in epidemiology2022

Linguistic spin in randomized controlled trials about age-related macular degeneration.

Nienke Veldhuis, Myrthe A Nuijts, Luka Isphording, Felicia V Y L Lee-Kong, Saskia M Imhof, Inge Stegeman

Open access · diamondAbstract read
In one paragraph

Article in Frontiers in epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nienke VeldhuisFaculty of Medicine, Utrecht University, Utrecht, Netherlands.
Myrthe A NuijtsDepartment of Ophthalmology, University Medical Center Utrecht, Utrecht, Netherlands.
Luka IsphordingFaculty of Medicine, Utrecht University, Utrecht, Netherlands.
Felicia V Y L Lee-KongFaculty of Medicine, Utrecht University, Utrecht, Netherlands.
Saskia M ImhofDepartment of Ophthalmology, University Medical Center Utrecht, Utrecht, Netherlands.
Inge StegemanDepartment of Ophthalmology, University Medical Center Utrecht, Utrecht, Netherlands.
University Medical Center Utrecht · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the prevalence, type and extent of linguistic spin in randomized controlled trials (RCTs) exploring interventions in patients with age-related macular degeneration (AMD), as well as to investigate whether study variables were correlated with linguistic spin. Study design and setting: PubMed was searched from 2011 to 2020 to identify RCTs including patients with AMD. Two authors independently assessed a total of 96 RCTs. Linear regression analyses were performed to investigate whether linguistic spin was correlated with predefined study variables. Results: Linguistic spin was found in 61 of 96 abstracts (63.5%) and in 90 of 96 main texts (93.8%). Use of words pointing out the beneficial effect of a treatment and the use of '(statistically) significant/significance' without reporting a Conclusion: A high prevalence and extent of linguistic spin in RCTs about AMD was found. We highlighted the importance of objective reporting and awareness of linguistic spin among ophthalmologists and other readers.

Indexed as

age-related macular degeneration (AMD)linguistic spinophthalmologyoverinterpretationrandomized controlled trial

Identifiers

PMID38455287
PMCPMC10910936
OpenAlexW4307679343

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.