Evidence map›Paper›PMID 38455224›Full record

ArticleFood science & nutrition2024

Isolation of phenolic compounds from eco-friendly white bee propolis: Antioxidant, wound-healing, and anti-Alzheimer effects.

Adem Necip, Ibrahim Demirtas, Seçil Erden Tayhan, Mesut Işık, Sema Bilgin, İsmail Furkan Turan, Yaşar İpek, Şükrü Beydemir

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. WildFood science & nutrition · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Green Extraction Strategies and Bioactivity ofPlants (Basel, Switzerland) · 2025
    Article
  12. Engineering yeast to produce fraxetin from ferulic acid and lignin.Applied microbiology and biotechnology · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Adem NecipDepartment of Pharmacy Services, Vocational School of Health Services Harran University Şanlıurfa Türkiye.ORCID https://orcid.org/0000-0002-2092-7829
Ibrahim DemirtasDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy Ondokuz Mayıs University Samsun Türkiye.ORCID https://orcid.org/0000-0001-8946-647X
Seçil Erden TayhanDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy Tokat Gaziosmanpasa University Tokat Türkiye.ORCID https://orcid.org/0000-0001-8473-5896
Mesut IşıkDepartment of Bioengineering, Faculty of Engineering Bilecik Seyh Edebali University Bilecik Türkiye.ORCID https://orcid.org/0000-0002-4677-8104
Sema BilginDepartment of Medical Laboratory Techniques, Vocational School of Health Services Gaziosmanpasa University Tokat Türkiye.ORCID https://orcid.org/0000-0001-5921-5434
İsmail Furkan TuranDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy Tokat Gaziosmanpasa University Tokat Türkiye.
Yaşar İpekPlant Research Laboratory-B, Department of Chemistry, Faculty of Science Cankiri Karatekin University Cankiri Türkiye.
Şükrü BeydemirDepartment of Biochemistry, Faculty of Pharmacy Anadolu University Eskişehir Türkiye.ORCID https://orcid.org/0000-0003-3667-6902
Tokat Gaziosmanpaşa Üniversitesi · TRAnadolu University · TRBilecik Şeyh Edebali Üniversitesi · TRÇankırı Karatekin University · TRHarran University · TROndokuz Mayıs University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents the first findings regarding extraction, isolation, enzyme inhibition, and antioxidant activity. The oral mucosal wound-healing process was investigated using propolis water extract (PWE) incubation with gingival fibroblast cells and concluded that propolis was effective on the oral mucosal wound-healing pattern compared to untreated controls. Additionally, phenolic compounds (fraxetin, apigenin, galangin, pinobanksin, chrysin, etc.) were isolated from propolis, and their chemical structures were elucidated using comprehensive spectroscopic methods. The antioxidant and anti-Alzheimer potential activities of PWE and some isolated compounds were screened and revealing their inhibitory effects on acetylcholinesterase (AChE) with IC

Indexed as

anti‐Alzheimerantioxidant capacityisolation of phenolicsphytochemicalpropoliswound‐healing

Identifiers

PMID38455224
PMCPMC10916560
OpenAlexW4389484412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.