Evidence map›Paper›PMID 38454937›Full record

ArticleRSC advances2024

Anticancer evaluations of iodoquinazoline substituted with allyl and/or benzyl as dual inhibitors of EGFR

Ahmed K B Aljohani, Khaled El-Adl, Basmah Almohaywi, Omar M Alatawi, Marwa Alsulaimany, Ahmed El-Morsy, Sara A Almadani, Hussam Y Alharbi, Majed S Aljohani, Felemban Athary Abdulhaleem M and 2 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Rationale,RSC advances · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Ahmed K B AljohaniPharmacognosy and Pharmaceutical Chemistry Department, College of Pharmacy, Taibah University Al-Madinah Al-Munawarah 41477 Saudi Arabia eladlkhaled74@azhar.edu.eg khaled.eladl@hu.edu.eg eladlkhaled74@yahoo.com.ORCID https://orcid.org/0000-0003-2332-1125
Khaled El-AdlChemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development Cairo Egypt.ORCID https://orcid.org/0000-0002-8922-9770
Basmah AlmohaywiDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University Abha 61421 Saudi Arabia.ORCID https://orcid.org/0000-0001-6389-3051
Omar M AlatawiDepartment of Chemistry, Faculty of Science, University of Tabuk Tabuk 47512 Saudi Arabia.
Marwa AlsulaimanyDepartment of Pharmacognosy & Pharmaceutical Chemistry, College of Pharmacy, Taibah University Medina 42353 Saudi Arabia.
Ahmed El-MorsyPharmaceutical Chemistry Department, College of Pharmacy, The Islamic University Najaf Iraq.
Sara A AlmadaniDepartment of Pharmacology and Toxicology, College of Pharmacy, Taibah University Medina 42353 Saudi Arabia.
Hussam Y AlharbiDepartment of Chemistry, Faculty of Science, Taibah University Yanbu Saudi Arabia.ORCID https://orcid.org/0009-0008-9682-1079
Majed S AljohaniDepartment of Chemistry, Faculty of Science, Taibah University Yanbu Saudi Arabia.
Felemban Athary Abdulhaleem MBiology Department, Faculty of Science, Umm Al-Qura University Makkah 21955 Saudi Arabia.
Hanan E M OsmanBiology Department, Faculty of Science, Umm Al-Qura University Makkah 21955 Saudi Arabia.
Samy MohamadyPharmaceutical Chemistry Department, Faculty of Pharmacy, The British University in Egypt Cairo Egypt.
Taibah University · SAAl-Azhar University · EGBritish University in Egypt · EGIraqi University · IQKing Khalid University · SAUmm al-Qura University · SAUniversity of Tabuk · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fifteen new iodoquinazoline derivatives, 5a,b to 18, are reported in this study and their anticancer evaluation as dual inhibitors of EGFR

Identifiers

PMID38454937
PMCPMC10916743
OpenAlexW4392523289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.