SynthesisCritical care (London, England)2024
Accuracy of respiratory muscle assessments to predict weaning outcomes: a systematic review and comparative meta-analysis.
Synthesis in Critical care (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association Between Diaphragm Ultrasound Measures and Extubation Outcomes in Neonates: A Systematic Review and Meta-Analysis.Pediatric pulmonology · 2026Pooled it
- Respiratory muscle dysfunction in mechanical ventilation: a systematic review and meta-analysis of biological mechanisms.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Pooled it
- The effect of remimazolam combined with low-dose propofol on diaphragmatic function in patients undergoing hysteroscopic surgery: a randomized clinical trial.BMC anesthesiology · 2025Trial
- Aligning prediction targets before ranking diaphragm ultrasound parameters in AECOPD.Critical care (London, England) · 2026Article
- Early Measurement of Quadriceps Response to Neuromuscular Electrical Stimulation to Identify Future ICU-Acquired Weakness.Critical care medicine · 2026Observational
- Application of bedside ultrasound assessment of diaphragmatic function in preparing tracheostomised patients for ventilator liberation and decannulation: a narrative review.Journal of thoracic disease · 2026Review
- Liberation from Non-Invasive Ventilation in Complex Intensive Care Unit Patients.Journal of clinical medicine · 2026Review
- Diagnostic accuracy of tests for assessing readiness for liberation from mechanical ventilation in adults: an overview of reviews.Journal of intensive care · 2026Review
- Beyond blood gases: diaphragm-guided sequential non-invasive ventilation for COPD with type II respiratory failure.Frontiers in medicine · 2026Review
- The diaphragm-intercostal index for predicting weaning failure in mechanically ventilated patients: a prospective cohort study.Frontiers in medicine · 2026Article
- Construction and validation of a risk prediction model for early ventilator-induced diaphragm dysfunction in mechanically ventilated patients.Frontiers in medicine · 2026Article
- The invasive and non-invasive monitoring of inspiratory effort and drive during assisted mechanical ventilation.Annals of intensive care · 2026Review
- Impact of ABCDE bundle nursing on pediatric respiratory distress syndrome under nasal continuous positive airway pressure therapy.Pakistan journal of medical sciences · 2025Article
- Tissue Doppler Imaging in Acute and Critical Care: Enhancing Diagnostic Precision.Medicina (Kaunas, Lithuania) · 2025Review
- Lung ultrasound score versus HACOR score as a predictor for weaning outcome in patients at high risk for extubation failure.Lung India : official organ of Indian Chest Society · 2025Article
- Influence of clinical severity and ventilation time on the use of timed inspiratory effort (TIE) as a predictor of success in ventilatory weaning.Journal of thoracic disease · 2025Article
- Reply to: Diaphragm excursion and diaphragm thickening fraction: commonality and conflict.European respiratory review : an official journal of the European Respiratory Society · 2025Article
- Exploring the adoption of diaphragm and lung ultrasound (DLUS) by physiotherapists, physical therapists, and respiratory therapists: an updated scoping review.The ultrasound journal · 2025Review
- Ventilation distribution during spontaneous breathing trials predicts liberation from mechanical ventilation: the VISION study.Critical care (London, England) · 2025Article
- Multimodal diaphragmatic ultrasound indicators in healthy adults: reliability and consistency observation by ultrasound physician and critical care physician.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundSeveral bedside assessments are used to evaluate respiratory muscle function and to predict weaning from mechanical ventilation in patients on the intensive care unit. It remains unclear which assessments perform best in predicting weaning success. The primary aim of this systematic review and meta-analysis was to summarize and compare the accuracy of the following assessments to predict weaning success: maximal inspiratory (PImax) and expiratory pressures, diaphragm thickening fraction and excursion (DTF and DE), end-expiratory (Tdi
methodsMedline (via Pubmed), EMBASE, Web of Science, Cochrane Library and CINAHL were comprehensively searched from inception to 04/05/2023. Studies including adult mechanically ventilated patients reporting data on predictive accuracy were included. Hierarchical summary receiver operating characteristic (HSROC) models were used to estimate the SROC curves of each assessment method. Meta-regression was used to compare SROC curves. Sensitivity analyses were conducted by excluding studies with high risk of bias, as assessed with QUADAS-2. Direct comparisons were performed using studies comparing each pair of assessments within the same sample of patients.
resultsNinety-four studies were identified of which 88 studies (n = 6296) reporting on either PImax, DTF, DE, Tdi
conclusionsDTF and DE are superior to PImax and DTF seems to have the highest accuracy among all included respiratory muscle assessments for predicting weaning success. Further studies aiming at identifying the optimal threshold of DTF to predict weaning success are warranted.
trial registrationPROSPERO CRD42020209295, October 15, 2020.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.