Evidence map›Paper›PMID 38454284›Full record

ArticleThe journal of international advanced otology2024

Has Coranavirus Disease 2019 Changed the Incidence and Outcome of Bell's Palsy?

Luis Lassaletta, Isabel Sánchez-Cuadrado, Teresa Mato-Patino, Julio Peñarrocha, María Angélica Rivera-Núñez, Rosario María Torres Santos-Olmo, Javier Gavilán, José Manuel Morales-Puebla, COVID ORL HULP Collaborative Group

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Article in The journal of international advanced otology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Luis LassalettaDepartment of Otorhinolaryngology, La Paz University Hospital, Madrid, Spain, IdiPAZ Research Institute, Madrid, Spain, Biomedical Research Networking Centre on Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain.
Isabel Sánchez-CuadradoDepartment of Otorhinolaryngology, La Paz University Hospital, Madrid, Spain, IdiPAZ Research Institute, Madrid, Spain.
Teresa Mato-PatinoDepartment of Otorhinolaryngology, La Paz University Hospital, Madrid, Spain.
Julio PeñarrochaDepartment of Otorhinolaryngology, La Paz University Hospital, Madrid, Spain.
María Angélica Rivera-NúñezDepartment of Emergency, La Paz University Hospital, Madrid, Spain.
Rosario María Torres Santos-OlmoDepartment of Emergency, La Paz University Hospital, Madrid, Spain.
Javier GavilánDepartment of Otorhinolaryngology, La Paz University Hospital, Madrid, Spain.
José Manuel Morales-PueblaDepartment of Otorhinolaryngology, La Paz University Hospital, Madrid, Spain, IdiPAZ Research Institute, Madrid, Spain, Biomedical Research Networking Centre on Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain.
COVID ORL HULP Collaborative GroupLa Paz University Hospital, Madrid, Spain.
Hospital Universitario La Paz · ESHospital La Paz Institute for Health Research · ESCentre for Biomedical Network Research on Rare Diseases · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObjectives: (1) To determine whether the incidence of Bell's Palsy (BP) increased during the pandemic. (2) To investigate whether the outcomes of patients with BP and COVID-19 infection or vaccination differ from those in the pre-pandemic era.

methodsPatients with BP were studied in 2 periods retrospectively (March 2021-March 2022 and August 2018-August 2019). A prospective study from March 2021 to March 2022 was also performed. Primary outcome was grade ≤Ⅱ in the House-Brackmann (HB) and/or >70 in the Sunnybrook facial grading system (SFGS) scales at the 12-week visit. Reverse transcriptase polymerase chain reaction (PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enzyme-linked immunosorbent assay-based SARS-CoV-2 immuonoglobulin G (IgG) test (blood) were measured.

resultsAbout 162 and 196 patients with BP were identified between March 2021 and March 2022 and August 2018 and August 2019, respectively. Forty-seven patients (29%) entered the prospective study; 85% had HB grades I or II, while 92% had an SFGS score of 71-100 at the last visit. Only 3 patients (6.5%) had a positive PCR during the initial episode, whereas 35 patients (77%) had positive IgG SARS-CoV-2. There was no association between positive PCR and facial function outcomes. Of the 162 patients, 105 (67%) had received COVID-19 vaccine. In 23 of them (22%), the paralysis appeared within the first 30 days after a vaccine dose.

conclusionCoronavirus disease 2019 did not increase the incidence of BP. A direct association between the coronavirus and BP outcome cannot be established. The considerable number of patients developing BP within the first month suggests a possible association between COVID-19 vaccines and BP.

Indexed as

Bell PalsyCOVID-19Facial ParalysisCOVID-19 VaccinesHumansImmunoglobulin GIncidenceProspective StudiesRetrospective StudiesSARS-CoV-2COVID-19 VaccinesImmunoglobulin G

Identifiers

PMID38454284
PMCPMC10895820
OpenAlexW4393132630

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.