Evidence map›Paper›PMID 38454132›Full record

ArticleBone marrow transplantation2024

Late-onset pulmonary complications following allogeneic hematopoietic cell transplantation in pediatric patients: a prospective multicenter study.

Véronique Houdouin, Jean Christophe Dubus, Sophie Guilmin Crepon, Fanny Rialland, Bénedicte Bruno, Charlotte Jubert, Philippe Reix, Marlène Pasquet, Catherine Paillard, Dalila Adjaoud and 7 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Véronique HoudouinUniversité de Paris Cité, AP-HP, Hôpital Robert Debré, Service de Pneumopédiatrie, RESPIRARE, INSERM U976, Paris, France. veronique.houdouin@aphp.fr.ORCID 0000-0002-6062-1293
Jean Christophe DubusUniversité Aix-Marseille, AP-HM, Hôpital universitaire Timone-Enfants, Service de Pneumopédiatrie, MEPHI, Méditerranée-Infection, Marseille, France.
Sophie Guilmin CreponAP-HP, Hôpital Robert Debré, Unité d'Epidémiologie Clinique, Inserm, CIC-EC 1426, Paris, France.
Fanny RiallandHôpital de la mère et l'enfant, Service d'hématologie pédiatrique, Nantes, France.ORCID 0000-0002-3136-6270
Bénedicte BrunoHôpital Jeanne de Flandre, Service d'hématologie pédiatrique, Lille, France.
Charlotte JubertCentre hospitalo-universitaire de Bordeaux, Service d'hématologie pédiatrique, Bordeaux, France.
Philippe ReixUniversité Lyon 1, Hôpital Femme Mère Enfant, Service de pneumologie, allergologie, mucoviscidose, CNRS, Laboratoire de Biométrie et biologie Evolutive UMR, 5558, Villeurbanne, France.
Marlène PasquetCentre hospitalo-universitaire de Toulouse Purpan, Hôpital des enfants, Service d'immuno-hémato-oncologie pédiatrique, INSERM U1037, Toulouse, France.
Catherine PaillardCentre hospitalo-universitaire de Strasbourg, Service d'hématologie pédiatrique, Strasbourg, France.
Dalila AdjaoudCentre hospitalo-universitaire de Grenoble, Service d'hématologie pédiatrique, Grenoble, France.
Cyril SchweitzerCentre hospitalo-universitaire de Nancy, Service de Physiologie respiratoire Pédiatrique, Nancy, France.ORCID 0000-0003-0895-774X
Muriel Le BourgeoisAP-HP, Hôpital Necker Enfants Malades, Service de pneumologie pédiatrique, Paris, France.
Justine PagesAP-HP, Hôpital Robert Debré, Unité d'Epidémiologie Clinique, Inserm, CIC-EC 1426, Paris, France.
Adyla YacoubiAP-HP, Hôpital Robert Debré, Unité d'Epidémiologie Clinique, Inserm, CIC-EC 1426, Paris, France.
Jean Hugues DalleUniversité de Paris Cité, AP-HP, Hôpital Robert Debré, Service d'hématologie pédiatrique, Paris, France.
Anne BergeronUniversité de Genève, Hôpitaux Universitaires de Genève, Genève, Suisse.ORCID 0000-0003-2156-254X
Christophe DelclauxUniversité de Paris Cité, AP-HP, Hôpital Robert Debré, Service de Physiologie Pédiatrique -Centre du Sommeil, INSERM NeuroDiderot, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary objective of our multicenter prospective study was to describe the incidence of late-onset non-infectious pulmonary complications (LONIPCs) in children undergoing hematopoietic cell transplantation (HCT) using sensitive criteria for pulmonary function test (PFT) abnormalities including the non-specific pattern of airflow obstruction. Secondary objectives were to assess the factors associated with LONIPC occurrence and the sensitivity of the 2014 NIH-Consensus Criteria of bronchiolitis obliterans syndrome (BOS). PFT and clinical assessment were performed prior to HCT and at 6, 12, 24, and 36 months post-HCT. LONIPC diagnosis was validated by an Adjudication Committee. The study comprised 292 children from 12 centers. Thirty-two individuals (11%, 95% CI: 8-15%) experienced 35 LONIPCs: 25 BOS, 4 interstitial lung diseases, 4 organizing pneumonia and 2 pulmonary veno-occlusive diseases. PFT abnormalities were obstructive defects (FEV

Indexed as

Hematopoietic Stem Cell TransplantationAdolescentBronchiolitis ObliteransChildChild, PreschoolFemaleHumansInfantLung DiseasesMaleProspective StudiesRespiratory Function Tests

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.